Rational antibiotic use Flashcards
Tetracycline may be used in the following conditions EXCEPT
A. CAP (community-acquired pneumonia)
B. Cholera
C. Leptospirosis
D. TB
D
What advice will you give to a patient treated with tetracycline?
A. Tetracycline is relatively safe for pregnant women
B. Dairy products significantly reduce absorption
C. It is a good antibiotic for malaria
D. AOTA
B
Narrowest spectrum antibiotic
A. Meropenem
B. Oxacillin
C. Ofloxacin
D. Ceftriaxone
B
Promotion of antibiotic efflux is a common mechanism of which antibiotic:
A. Penicillin
B. Clindamycin
C. Tetracycline
D. Azithromycin
C
The penicillin resistant Streptococcus pneumoniae based on ARSP 2012 in the Philippines is
A. Higher
B. Lower
C. The same
B
Cotrimoxazole resistant Streptococcus pneumoniae and Haemophilus influenzae has:
A. Remained high
B. Remained low
C. Remained unchanged
A
Which is not a drug of choice for the treatment of Salmonella
A. Levofloxacin
B. Ampicillin
C. Cotrimoxazole
D. Chloramphenicol
A
The main steps to prevent antimicrobial resistance is/are:
A. Prevent infection
B. Diagnose and treat effectively
C. Use antimicrobials wisely
D. All of the above
D
Obtaining a positive culture of the ff. bacteria does NOT warrant antibiotic treatment:
A. S. aureus
B. Enterobacter sp.
C. Acinetobacter sp.
D. Corynebacterium sp.
D
A 64 year old male is diagnosed to have hospital-
acquired pneumonia. What would be the optimal dosing of Meropenem?
Time or concentration dependent?
Time-dependent
A 64 year old male is diagnosed to have hospital-
acquired pneumonia. What would be the optimal dosing of Meropenem?
Half-life: short or long?
Short
A 64 year old male is diagnosed to have hospital-
acquired pneumonia. What would be the optimal dosing of Meropenem?
Dosing?
2 g over 3 hrs q 8 hrs
A 3 month old baby is diagnosed to have sepsis. You plan to treat with Ampicillin and Gentamicin. What would be the optimal dosing of Gentamicin at 5
mg/kg/day for a 4 kg infant?
Time or conc. dependent?
Concentration-dependent
A 3 month old baby is diagnosed to have sepsis. You plan to treat with Ampicillin and Gentamicin. What would be the optimal dosing of Gentamicin at 5
mg/kg/day for a 4 kg infant?
Half life?
2-3 hrs; does not matter because it is concentration-dependent
A 3 month old baby is diagnosed to have sepsis. You plan to treat with Ampicillin and Gentamicin. What would be the optimal dosing of Gentamicin at 5
mg/kg/day for a 4 kg infant?
Dosing?
5 mg/kg once a day or 20 mg IV once a day (q 24 hours)
