Rate-Determining Enzymes - Metabolism

Question 1

What is the rate limiting step of Glycolysis

Answer 1

Phosphofructokinase-1 (PFK-1)

Question 2

What is the rate limiting step of Gluconeogenesis

Answer 2

Fructose-1,6-bisphosphatase

Question 3

What is the rate limiting step of TCA cycle

Answer 3

Isocitrate dehydrogenase

Question 4

What is the rate limiting step of Glycogenesis

Answer 4

Glycogen synthase

Question 5

What is the rate limiting step of Glycogenolysis

Answer 5

Glycogen phosphorylase

Question 6

What is the rate limiting step of HMP shunt

Answer 6

Glucose-6-phosphate dehydrogenase (G6PD)

Question 7

What is the rate limiting step of De novo pyrimidine synthesis

Answer 7

Carbamoyl phosphate synthetase II

Question 8

What is the rate limiting step of De novo purine synthesis

Answer 8

Glutamine-phosphoribosylpyrophosphate (PRPP) amidotransferase

Question 9

What is the rate limiting step of Urea cycle

Answer 9

Carbamoyl phosphate synthetase I

Question 10

What is the rate limiting step of Fatty acid synthesis

Answer 10

Acetyl-CoA carboxylase (ACC)

Question 11

What is the rate limiting step of Fatty acid oxidation

Answer 11

Carnitine acyltransferase I

Question 12

What is the rate limiting step of Ketogenesis

Answer 12

HMG-CoA synthase

Question 13

What is the rate limiting step of Cholesterol synthesis

Answer 13

HMG-CoA reductase