Rapid Review1

Question 1

Apical displacement of TV leaflets, decreased ventricular volume, atrialization of right ventricle

Answer 1

Epstein anomaly Litium in pregnancy

Question 2

Patchy areas of endocardial fibrosis and subendocardial vacuolozation

Answer 2

Chronic ischemic heart disease

Question 3

DTAP induces what immune response?

Answer 3

Produce neutrolizing AB against the B subunit of the exotoxin that prevents binding via IgG circulating proteins

Question 4

Cancer ass. with H. Pylori

Answer 4

intestinal gastric adenocarcinoa, MALT

Question 5

Positive Cl- test in a neonate that has not passed meconium. What is the embryological defect? What other pathologies is this related to?

Answer 5

Males wit cystic fibrosis:

Infertile (kartanger) –> improper development of the mesonephric (Wolffian) duct system,

which most often leads to a defective vas deferens.

Other derivatives

vas deferens,

epididymis,

seminal vesicles, and

ejaculatory duct,

ureter,

renal pelvis,

calyces, and

collecting tubules

Additional abnormalities in cystic fibrosis include exocrine pancreas deficiency, late-onset puberty, chronic sinusitis, and chronic upper respiratory tract infections.

Question 6

Situs inversus, chronic sinusitis, bronchiectasis, infertility

Answer 6

Kartanger syndrom

Question 7

most commonly implicated serovar in cases of food poisoning

Answer 7

Salmonella enterica enteritidis

Question 8

Hektoen enteric agar

Answer 8

Differentiates Salmonella from Shigella. Salmonella produces hydrogen sulfide. The presence of thiosulfate or ferric ammonium citrate in the medium produces a black precipitate in the presence of H2S, allowing Shigella – which does not produce H2S, and appears as green colonies – to be distinguished from Salmonella – which does produce hydrogen sulfide and appears as black colonies.[2]

Question 9

Non fusion of the urogenital folds in males vs females

Answer 9

vestibule of the vagina but in males hypospadias

Hypospadias is more common than epispadias. Associated with inguinal hernia and cryptorchidism.

Hypo is below.

Abnormal opening of penile urethra on ventral surface of penis due to failure of urethral folds to fuse.

Question 10

Alternative therapy for TMP-SMX for prophylactic treatment of pneumo. jirovi

Answer 10

Dapsone

Question 11

Adverse reactions of dapson

Answer 11

hemolytic anemia: Bite cells

Question 12

Drugs that precipitate G6P difficiency “Hemolysis IS D PAIN”

Answer 12

Isoniazid,

Sulfonamides,

Dapsone,

Primaquine,

Aspirin,

Ibuprofen,

Nitrofurantoin (sulfa drugs, antimalarials, infections, fava beans)

Question 13

Management of drug induced parkinsonism

Answer 13

Anticholinergics trihexyphenidyl benztropine

Question 14

What and where is Ang 1 converted to 2?

Answer 14

small vessels

Question 15

Protein that recognizes stop codon and terminate protein synthesis

Answer 15

Releasing factor

Question 16

Hematuria, back pain and fevor. What type of NSAID can be used that doesn’t affect platelet aggregation?

Answer 16

Celecoxib

Question 17

Following CHF, will the level of ANG 2 be higher in the pulmonary artery or vein? Why

Answer 17

pulmonary vein

Question 18

In CHF, Arteriolar resistance is ____ (increased or decreased?)

Answer 18

increased

Question 19

How do disinfectants such as isopropanol work

Answer 19

disruption of cell membranes

• denaturation of proteins
• not sporicidal
• tuberculocidal, fungicidal, virucida

Question 20

Primary source of glucose for the first 12-18 hours. After this time period what is the primary source?

Answer 20

Glycogenolysis–>Glucogenolysis

Question 21

Affect of spironolactone on the DCT

Answer 21

decrease in hydrogen ion secretion