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Rapid Step Review > Rapid Review 3 > Flashcards

Rapid Review 3 Flashcards

1
Q

anti-centromere antibodies

A

CREST

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2
Q

anti-desmoglein 3 antibodies

A

pemphigus vulgaris

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3
Q

anti-GBM antibodies

A

Goodpasture’s

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4
Q

anti-histone antibodies

A

drug-induced lupus

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5
Q

anti-IgG antibodies

A

RA

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6
Q

anti-mitochondria antibodies

A

primary biliary cirrhosis

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7
Q

c-ANCA

A

Wegener’s

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8
Q

p-ANCA

A

Churg-Strauss, microscopic polyangiitis

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9
Q

ANA, anti-smith, anti-dsDNA

A

SLE

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10
Q

anti-platelet antibodies

A

idiopathic thrombocytopenic purpura

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11
Q

anti-topoisomerase antibodies

A

diffuse systemic scleroderma

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12
Q

anti-transglutaminase/gliadin/endomysial antibodies

A

Celiac Disease

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13
Q

apple core lesion on abdominal x-ray

A

left-sided colon cancer

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14
Q

azurophilic peroxidase-positive granular inclusions in granulocytes and myeloblasts

A

Auer Rods (AML)

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15
Q

bacitracin sensitive

A

Strep pyogenes (GAS)

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16
Q

bacitracin resistant

A

Strep agalactiae (GBS)

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17
Q

bamboo spine on X-ray

A

ankylosing spondylitis

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18
Q

basophilic nuclear remnants in RBCs

A

Howell-Jolly bodies

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19
Q

basophilic stippling of RBCs

A

lead poisoning or sideroblastic anemia

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20
Q

bloody tap on LP

A

subarachnoid hemorrhage

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21
Q

boot shaped heart on X-ray

A

RVH, Tetralogy of Fallot

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22
Q

branching G+ rods with sulfur granules

A

Actinomyces israelii

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23
Q

bronchogenic apical lung tumor on imaging

A

Pancoast tumor

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24
Q

brown tumor of bone

A

hyperparathyroidism or osteitis fibrosa cystica

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25
Q

cardiomegaly with apical atrophy

A

Chagas’ disease

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26
Q

cellular crescents in Bowman’s capsule

A

RPGN

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27
Q

chocolate cyst of ovary

A

endometriosis

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28
Q

circular grouping of dark tumor cells surrounding pale neurofibrils

A

Homer-Wright Rosettes (medulloblastoma)

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29
Q

colonies of mucoid Pseudomonas in lungs

A

cystic fibrosis

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30
Q

decreased alpha-fetoprotein in amniotic fluid/maternal serum

A

Down Syndrome

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31
Q

degeneration of dorsal column nerves

A

tabes dorsalis or subacute combined degeneration

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32
Q

depigmentation of neurons in substantia nigra

A

Parkinson’s disease

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33
Q

desquamated epithelium casts in sputum

A

Curschmann’s spirals (from asthma)

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34
Q

disarrayed granulosa cells in eosinophilic fluid

A

Call-Exner bodies (granulosa-theca cell tumor of ovary)

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35
Q

dysplastic squamous cervical cells with nuclear enlargement and hyperchromasia

A

koilocytes (HPV)

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36
Q

enlarged cells with intranuclear inclusion bodies

A

Owl’s eye appearance of CMV

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37
Q

enlarged throid cells with ground-glass nuclei

A

Orphan Annie’s eyes nuclei from papillary carcinoma of the thyroid

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38
Q

eosinophilic cytoplasmic inclusion in liver cell

A

Mallory bodies

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39
Q

eosinophilic cytoplasmic inclusion in nerve cell

A

Lewy Body

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40
Q

eosinophilic globule in liver

A

Councilman body in toxic or viral hepatitis/yellow fever

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41
Q

eosinophilic inclusion bodies in cytoplasm of hippocampal nerve cells

A

Negri bodies of rabies

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42
Q

extracellular amyloid deposition in gray matter in brain

A

senile plaques (Alzheimer’s Disease)

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43
Q

giant B cells with bilobed nuclei with prominent inclusions

A

Reed-Sternberg cells of Hodgkin’s lymphoma

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44
Q

glomerulus-like structure surrounding vessel in germ cells

A

Schiller-Duval bodies (yolk sac tumor)

45
Q

hair on end (crew cut) appearance on X-ray

A

beta-thalassemia, sickle cell anemia

46
Q

hCG elevated

A

choriocarcinoma, hydatidiform mole

47
Q

heart nodules (granulomatous)

A

Aschoff bodies (rheumatic fever)

48
Q

heterophile antibodies

A

infectious mono

49
Q

hexagonal, double-pointed, needle-like crystals in bronchial secretions

A

Charcot-Leyden crystals; asthma

50
Q

D-dimers

A

DVT, pulmonary embolism, DIC

51
Q

hilar lymphadenopathy, peripheral granulomatous lesion in middle or lower lung lobes

A

Ghon complex (primary TB)

52
Q

honeycomb lung

A

IPF

53
Q

migrating thrombophlebitis

A

Trousseaus’s syndrome (underlying adenocarcinoma of pancreas or lung)

54
Q

hypersegmented neutrophils

A

B12 or folate deficiency

55
Q

hypertension, hypokalemia, metabolic alkalosis

A

Conn’s syndrome

56
Q

hypochromic, microcytic anemia

A

iron deficiency anemia lead poisoning, beta-thal, anemia of chronic disease

57
Q

increased alpha-fetoprotein in amniotic fluid/maternal serum

A

neural tube defects

58
Q

increased uric acid levels

A

gout, Lesch-Nyhan syndrome, tumor lysis syndrome, loop and thiazide diuretics

59
Q

intranuclear eosinophilic droplet-like bodies

A

Cowdry type A bodies (HSV or CMV)

60
Q

iron-containing nodules in alveolar septum

A

ferruginous bodies (asbestosis)

61
Q

keratin pearls on a skin biopsy

A

squamous cell carcinoma

62
Q

large lysosomal vesicles in phagocytes + immunodeficiency

A

Chediak-Higashi Disease (congenital failure of phagolysosome formation)

63
Q

lead pipe appearance of colon on barium enema X-ray

A

ulcerative colitis (due to loss of haustra)

64
Q

linar appearance of IgG deposition on glomerular basement membrane

A

Goodpasture’s

65
Q

low serum ceruloplasmin

A

Wilson’s Disease

66
Q

lumpy bumpy appearance of glumeruli on immunofluorescence

A

PSGN

67
Q

lytic bone lesions

A

Multiple Myeloma

68
Q

mammary gland cyst

A

fibrocystic change of the breast

69
Q

monoclonal antibody spike

A

MM, MGUS, Waldenstrom’s, primary amyloidosis

70
Q

mucin-filled cell with peripheral nucleus

A

signet ring

71
Q

narrowing of bowel lumen on barium x-ray

A

string sign (Crohn’s)

72
Q

necrotizing vasculitis in lungs and kidneys

A

Wegener’s

73
Q

needle-shaped, negatively birefringent crystals

A

gout

74
Q

nodular hyaline deposits in glomeruli

A

Kimmelstiel-Wilson nodules

75
Q

Novobiocin sensitive

A

Staph epidermidis

76
Q

Novobiocin resistant

A

Staph saprophyticus

77
Q

nutmeg appearance of liver

A

right heart failure

78
Q

onion skin periosteal reaction

A

Ewing’s sarcoma

79
Q

optochin sensitive

A

Strep pneumoniae

80
Q

optochin resistant

A

Strep viridans

81
Q

periosteum raised from bone, creating triangular area

A

Codman’s triangle (osteosarcoma, Ewing’s sarcoma)

82
Q

podocyte effacement

A

MCD

83
Q

protein aggregates in neurons

A

neurofibrillary tangles, Pick’s bodies, (hyperphosphorylated Tau)

84
Q

psammona bodies

A

meningiomas, papillary thyroid carcinoma, mesothelioma, papillary serous carcinoma of the endometrium and ovary

85
Q

pseduopalisading tumor cells on brain biopsy

A

GBM

86
Q

RBC casts in urine

A

acute glomerulonephritis

87
Q

rectangular, crystal-like, cytoplasmic inclusions in Leydig cells

A

Reinke crystals (sertoli-leydig cell tumor)

88
Q

renal epithelial casts in urine

A

acute toxic/viral nephrosis

89
Q

rhomboid crystals, positively birefringent

A

pseudogout (calcium pyrophosphate dihydrate crystals)

90
Q

rib notching

A

coarctation of aorta

91
Q

ring-enhancing brain lesion in AIDS

A

Toxoplasma gondii, CNS lymphoma

92
Q

sheets of medium-sized lymphoid cells with scattered pale, tingible body-laden macrophages

A

Burkitt’s lymphoma; t(8;14)

93
Q

silver-staining spherical aggregation of tau proteins in neurons

A

Pick bodies

94
Q

soap bubble in femur or tibia on X-ray

A

Giant cell tumor of bone

95
Q

spikes on basement membrane, dome like subepithelial deposits

A

membranous glomerulonephritis

96
Q

stacks of RBCs

A

Rouleaux formation (MM)

97
Q

stippled vaginal epithelial cells

A

clue cells from Gardnerella vaginalis

98
Q

tennis racked shaped cytoplasmic organelles

A

Birbeck granules in Langerhans cell histiocytosis

99
Q

thrombi made of white/red layers

A

lines of Zahn

100
Q

thumb sign on lateral X-ray

A

epiglottitis caused by H. flu

101
Q

thryoidization of kidney

A

chronic bacterial pyelonephritis

102
Q

tram-track appearance of capillary loops of glomerular basement membranes

A

MPGN

103
Q

triglyceride accumulation in liver cell vacuoles

A

fatty liver disease

104
Q

waxy casts with very low urine flow

A

chronic end stage renal disease

105
Q

WBC casts in urine

A

acute pyelonephritis

106
Q

smudge cells

A

CLL

107
Q

wire loop glomerular capillary appearance

A

lupus nephropathy

108
Q

yellowish CSF

A

xanthochromia due to SAH

Rapid Step Review (4 decks)

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