random q Flashcards
first test in patient with suspected SLE
urinalysis
a patient with antiphospholipd syndrome has a PE what is the best treatment
life long warfarin
schirmer test
placing a strip of filter paper under the lower eye lid
used in sjogrens syndrome
schober test
measure of spinal flexion
used in ankylosing spondylitis
schilling test
measure vit B12 absorption
in reactive arthritis is the joint usually positive for microorganisms
no
extra-articular manifestations common in the spondyloarthrides
achilles tendonitis
aortic valve incompetence
uveitis
dactylitis
Beighton scoring system consists of
passively touch the forearm with the thumb with the wrist in the flexed position (1 point for each side), passive hyperextension of the fingers or the little finger beyond 90 degrees (one point each hand), hyperextension of the elbows or knees beyond 10 degrees (one point for each) and the ability to touch the floor with both palms with the legs straight (one point). A score of four or more suggests hypermobility
initial investigation of choice for detecting renal involvement of vasculitis
urinalysis
classical radiological findings associated with osteoarthritis
loss of joint space
osteophyte formation
subchondral sclerosis
subchondral cysts
restricted rotation of the shoulder suggests?
adhesive capsulitis
tenderness in the heel on walking suggests?
plantar fasciitis
tenderness over the greater trochanter
trochancteric bursitis
tenderness over medial epicondyle
golfer’s elbow
tenderness over lateral epicondyle
tennis elbow
which antibody is associated with SLE
anti-DNA
which antibody is associated with systemic sclerosis
anti-centromere
which antibody is associated with sjogrens syndrome
anti-La
which antibody is associated with polymyositis
anti-Jo-1
injury to the anatomical snuff box is most likely to damage
radial artery
typical history of ankle fracture
inversion injury with rotational force applied to the foot
management of ankle fracture
conservative- cast or moonboot
operative- open reduction internal fixation
presentation of L5 radiculopathy
weakness of hip abduction
foot drop
management of gca
prednisolone 40-60mg
what are the connective tissue diseases
SLE
sjogrens
systemic sclerosis
anti-phospholipid syndrome
management of connective tissue diseases
treat symptomatically and monitor closely
in SLE- start hydroxychloroquine
limited systemic sclerosis presentation
C- calcinosis R- raynauds E- oesophageal dysmotility S- sclerodactyly T-telangiectasia pulmonary fibrosis = diffuse systemic sclerosis
antibody associated with limited systemic sclerosis
anti-centromere
antibody associated with diffuse systemic sclerosis
anti-Scl-70
presentation of anti-phospholipid syndrome
migraine
recurrent pregnancy loss
livedo resticularis
venous thrombosis
classic xray finding in pseudogout
chondrocalcinosis
nice guidelines for DMARDs
1st: monotherapy with methotrexate, leflunomide or sulfasalazine
2nd: two in combination
3rd: methotrexate plus biological therapy (usually tnf inhibitor)
safe DMARDs for pregancy
sulfasalazine
hydroxychloroquine
examples of anti-TNF inhibitors
adalimumab
infliximab
etanercept
golimumab
rituximab
anti-CD20 biological therapy
presentation of pagets disease
nerve entrapment
deformity of bone
fractures
raised serum alkaline phosphatase
management of pagets disease
oral bisphosphonates