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pharm > random med info > Flashcards

random med info Flashcards

1
Q

Anti clot ; antithrombotic drug classification

A

acute coronary syndrom MI
aspirin, inhibit platelet agregation= antiplatelet agents

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2
Q

anti clot

A
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3
Q

milirone indication

A

HF, cardiac transplant, hypertension

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4
Q

milirone SE

A

hypokalemia

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5
Q

Milirone ADR

A

ventricular tachy arrhytmias , cardiac ischemia, hypotension

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6
Q

Thiazide

A

treats hypertension

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7
Q

antihepersentives thiazides SE

A

hypokalemia = leg cramps

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8
Q

antianginal dont give to pts who have

A

thrombocytopenia
myastasia gravis

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9
Q

antiaginal monitor pts who have

A

heart blocks & pace makers

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10
Q

NE ADRs

A

myocardial ischemial & peripheral ischemia

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11
Q

NE Side effecfts

A

bradycardia

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12
Q

NE indications

A

hypotension,

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13
Q

ACE indications

A

severe HTN & HF

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14
Q

low TI means there is a small window between … & … aka …

A

effective & toxic dose , narrow TI

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15
Q

Digoxin in hf is preffered in pts with

A

AFIB

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16
Q

ACE considerations

A

K supplements/rich foods cough may occur consider ARB

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17
Q

ACE ADRs

A

cough & hyperkalemia

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18
Q

Ronalazine (SCB) indication

A

used to help with life threatening ventricular dysrithmias or for conversion of AFIB
3 classes: 1a, 1b, 1c

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19
Q

anticoagulant

A

prevent conversion of inactive prothrombin to active thrombin (PE, DVT)

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20
Q

Altapase

A

thrombolytic

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21
Q

Altapase indication

A

acute treatment of MI / ischemic stroke, massive PE, also for central line catheter

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22
Q

Altapase ADR

A

fatal, VS q5mins only in IV, monitor super bleeding risk

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23
Q

Altapase Considerations

A

never IM only IV injections
DONT GIVE IF: active internal /intracranial bleeding
HX of recent stroke
w/in 3 months has intracranial/ intraspinal surgery
any head trauma
neoplasm or AV malformation or aneurysm
uncontrolled HTN

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24
Q

Pradaxa indication
(thrombin inhibitor

A

prevents DVT and PE

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25
Q

Pradaxa ADRs

A

epidural & spinal hematoma

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26
Q

Pradaxa considerations

A

monitor unusual bleeding

27
Q

Pradaxa OD reversal

A

Idarucizumab

28
Q

RIvoraxaban indication

A

DVT, PE, MI, PAD

29
Q

Rivoraxaban ADR

A

epidural and spinal hematomas

30
Q

Rivoraxaban considerations

A

DONT give to pts with severe liver disease

31
Q

OD reversal of Rivoraxaban

A

Active charcoal & andexxa

32
Q

Epinephrine indications

A

VFIB ( pulseless)
anaphalasics

33
Q

Epinephrine SE

A

dizziness, anxiety, tremors, weakness, N/V/D

34
Q

Warfarin OD reversal

A

Vitamin K (phytonadione)

35
Q

Warfarin indications

A

DVT, PE, AFB, cardiac valve replacement, MI, or ischemic stroke

36
Q

Warfarin ADRs

A

fatal bleeding; highest incident for this

37
Q

Warfarin considerations

A

monitor PT & INR

38
Q

INR Therapeutic range in WARFARIN

A

NARROW TI of 2.0 - 3.5

39
Q

Warfarin should avoid

A

alcohol & grapefruit juice
straight razors use electric razors instead

40
Q

Warfarin contraindications

A

hemorrhagic hx
surgeries in eyes or CNS system
endocarditis
dissecting aorta
pregnant women

41
Q

Enoxaparin indication

A

DVT, MI (prevention)

42
Q

Enoxaparin ADRs

A

epidural & spinal hematomas => paralysis, hemorrhage, HITT

43
Q

Enoxaparin partial reversal is

A

protamine sulfate

44
Q

Enoxaparin considerations

A

administer subq= abdomen
increase bleeding risk =educate about falls

45
Q

Heparin antidote is

A

protamine sulfate

46
Q

Heparin ADRs

A

hemorrhage/bleeding, HYPOTENSION, HR, HIT, skin necrosis, thrombocytopenia

47
Q

what should you do if HIT is present during heparin administration

A

STOP med (heparin)

48
Q

Heparin considerations

A

AVOID NSAIDS
higher bleeding incidents in pts over 60 yrs
ensure women isnt pregnant

49
Q

Heparin indications

A

DVT, PE, central line or IV flushes

50
Q

Clopidogrel ADRs

A

risk for bleeding & liver dysfunction

51
Q

Clopidogrel considerations

A

avoid NSAIDS

52
Q

SE of CLOPIDOGREL

A

tinnitus
gastric irritation
unusual gum bleeding

53
Q

Aspirin indications

A

hx of PAD, MI, ischemic stroke
prophalaxis to decrease incident of MI, transient ischemic attacks, re-occlusion in coronary revascularization procedures & stent implants

54
Q

Aspirin ADRs

A

risk of bleeding, reduced effectiveness w/ liver dysfunction

55
Q

Aspirin SE

A

tinnitus
gum bleed
gastric irritation

56
Q

ASPRIN OD is

A

IRREVERSIBLE

57
Q

Aspirin considerations

A

DONT give to kids under 12 yrs= REYES syndrome
elderly risk of bleeds
stop 1 wk prior to surgery

58
Q

normal aPTT

A

1.5 - 2.5

59
Q

ARB ADR

A

hypotension
dizziness
andioedema
proteinuria

60
Q

platelets serves as surface for …

A

activation of clotting factors

61
Q

Factors Xa convert …

A

prothrombin to thrombin

62
Q

Fibrin retracts to …

A

from thrombus

63
Q

beta blockers

A

-lol

64
Q
A

pharm (8 decks)

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