Anti-Anginal Meds

Question 1

What results in MI

Answer 1

-O2 supply vs. O2demand
-plaque obstruct perfusion leads to decrease supply
-increase demand precipitated by exertion of stress

Question 2

Two types of Anginas

Answer 2

Stable Angina (CAD)
Unstable Angina (ACS)

Question 3

What does an Unstable Angina do ?

Answer 3

increases chest pain severity, frequency and duration

Question 4

Risk factors of Ischemic heart
disesase/angina

Answer 4

-HTN
-increase cholesterol diabetes
-Family Hx
-Stress
-Lack of exercise

Question 5

The FIRST LINE DRUGS as treatment and prophalaxis

Answer 5

Nitrates

Question 6

NITRATES
MOA

Answer 6

relieves angina by relaxing smooth muscle=vasodilation
-increase supply, decrease MVO2
-dilate cornary artery (relieves spasm)
-decreases preload (dilate veins)
-dilates arteries (decreases afterload) => decrease MVO2
-decreases intracellular CA causing smooth mucsle/vascular relaxation

Question 7

Organic Nitrates (3)

Answer 7

isosorbide dinitrate
isosorbide mononitrtrate
nitroglycerin

Question 8

Nitrates act on the …. and are…..

Answer 8

vein, venodilators

Question 9

Nitrates cardiac work

Answer 9

decrease preload, afterload, MVO2
decrease coronary spasm
increase blood flow

Question 10

CAD casues what kind of pain

Answer 10

chronic pain

Question 11

MI causes what kind of pain

Answer 11

acute pain

Question 12

Nitrates inidications:

Answer 12

used to relieve angina d/t CAD or prophylactically

Question 13

man i give up