Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

random > Random Mcqs > Flashcards

Random Mcqs Flashcards

1
Q

Medulloblastoma classified based on what pathways

N myc
W NT
SHH

A

Positive for GFAP

Astrocytoma
Oligodendroglioma
Ependymoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Rosenthal fibres

A

PILOCYTIC

ASTROCYTOMA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Alexander

A

Fibrinoid leucodystrophy

bifrontal wh matter inv

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Gtcs fisrt line agent

A

Valp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

AED not removed by dialysis

A

Phenytoin

Needs least dosage adjustment in renal failure

Asso with chorea also

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Giant cell arteritis

A

Painless vision loss
AION anterior ischemic ON

post ciliary opthal artery

Asso with migraineurs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

In Acute Coronary event and acute cardiogenic pulmonary edema reduce BP < 140 mm of Hg

Hypertensive encephalopathy: Reduce MAP 20-25% immediately

Hemorrhagic stroke with SBP > 180 : Reduce SBP to 130-180 mm of Hg range immediately.

A

Htn guidelines of management - European

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Hepatitis b Mc genotype

A

GENTOTYPE D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Adrenal tumor

A

Dheas > 7000

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Hypokalemia
Hypocalcemia
Hypo or hyper Mg

A

QT prolongation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

PML

A

Natalizumab

MMF

dimethyl fumarate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Abs safe in myasthenia

Amoxyclav

A

Harlequin appearance of orbit on Mri skull

Seen in coronal craniosynostosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

.The dural tail is thought to represent reactive change; however, it may also be due to tumor invasion.

Three criteria need to be met for a ‘positive’ dural tail sign: the tail should be seen on two successive images through the tumor,

it should taper away from the tumor,

and it must enhance more than the tumor.

A

This sign has been traditionally considered as highly specific for meningioma. However, it is seen only in 60% of meningiomas and has

also been reported in nonmeningiomatous lesions such as chloromas, primary CNS lymphomas, sarcoidosis, schwannomas, metastases, and syphilitic gummata.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

14-4-3

Cjd

Herpes

Multi infarct dementia

A

NFT

AD

Normal aging

Post enceohalititic Parkinson’s

PSP etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Miller Fischer test

NPH

MFS Brighton criteria

Normal conscious
Normal ncs
Csf abnormal

A

Lacunar strokes with maximum cognitive defects

Thalamus

Putamen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Early onset vs late onset AD

Early onset

Tauburden more in post neocortex
Relativ sparing of hippo
Non amnestic presentation Mc

A

Sporadic cjd

Cortical ribboning present

Flupirtine used for PRION

Antemortem diagnosis
Variant cjd

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

JME avoid CBZ

NTD RISK AEDS
VALP
CBZ

Folate decreases ntd by 50 percent

A

AT MCI stage no treatment helps to prevent it to progress to AD

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Meningioma

Positive for

Vimentin

Epithelial membrane antigen

Progesteron receptor

A

Prions spongiform change not seen in Familial fatal insomna

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Moll and wright criteria

A

Psoriatic arthropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

polycythemia

A

pruritus
Stroke
Headache
Increased b12

No bleeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Olfaction and hearing affected

A

Refsums

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Liver biopsy in hemochromatosis

A

Ferritin > 300

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Palatal myoclonus

Inf olives

A

Ocular myoclonus

Mollarets triangle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Yellow urine

A

Entacapone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Pawn ball megakaryocyte

A

AML

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Park 2/ Parkin mutation

A

AR

Absence of Lewy body

Dystonias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Bio safety level req for cjd pts

A

Level 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

DOWN BEAT NYSTAGMUS

A

SCA 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Prions

Spongiform changes in molecular layer of cbllum

Vacuoles in neuropil b/n cell bodies

GSS ataxia —- amyloid plaques +

A

Distinct strains exhibit distinct properties

Prpc rich in alfa than beta

Prpsc rich in beta

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Ocular tilt reaction

VESTIBULAR DYSFUNCTION of same side

A

Early onset gen dystonia Mc gene mut

TOR 1A

Mcc procedural memory loss — PD

Motor impersistence —- non dom frontal lobe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Mc presentation of meningovasc syphilis

Stroke

A

PML

Frontal cortex
Pons
Cbbllm ataxia

Mc presentation visual deficit
But optic nerve not involved

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Thomsen disease

A

AD myotonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Scn1 a

avoid lamo. Phenytoin

Scn 2a. / 8a

high dose phenytoin

A

Slc2a1. Glut 1

Aldh 7a1. Antiquitin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Astrocyte plaques CBD

oilgodendroglial coiled bodies
CBD
also in AD PSP

A

Compact. Crescentic inclusions

FTLD TDP type A

Diffuse granular inclusions

FTLD TDP TYPE B

long tortuous neurites

FTLD TDP type C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Boston battery

A

Ex of APHASIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

GSS vs CJD

dementia late in gss

A

FAMILIAL H C

Calcium fhc1

Na k atpase

Sodium fhc 3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Heyde syndrome

A

Aortic stenosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

MEDNIK syndrome

A

Cu metabolism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Smoking

A

major cause of copd

10 percent risk of I and H stroke

no risk in PD

increased risk of aortic aneurysm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

ANNA 1

Anti Ri

Anti amphysin Vgkc potassium Chanel ABs

A

Sensory neuronopathy

OPSOCLONUS Ri

Neuromyotonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Trail making test

A

To connect 25 numbered circles

Time taken to

to assess executive dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

REESE ELLSWORTH STAGING

A

Retinoblastoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

SHIMODA CLASSIFICATION

A

Neuroblastoma

45
Q

ROP leads to what in later life

A

Myopia

46
Q

Tests sensitive and specific to alcohol consumption

A

GGT > 35

CDT > 20 ( carb Defoe isn’t transferrin )

MCV > 91
Utica acid > 7 clue to alcohol use

47
Q

Risk of epilepsy

A

With stroke 50 percent

With penetrating trauma

30–50 percent

With closed head injury

5— 25 percent

48
Q

CMT 2

A

CMT 2 Mc gene MFN2

CMT 2c diaphragmatic palsy

49
Q

Alice in wonderland syndrome

A

Atypical ped migraine
With metamorphosia
Asso with temporal lobe epilepsy

50
Q

Abetalipoproteinemia

Because of defect in MTP

Not Apo B

A

Because of defect in MTP

Not Apo B

51
Q

CJD

A

Aggressive behaviour

painful sensory symptoms

Dementia

52
Q

Preferred Ab for SBP

A

Cefotaxime

53
Q

MC vasculitic neuropathy

A

common peroneal neuropathy

54
Q

Perivascular rosettes

A

Ependymoma

55
Q

Oligodendrocytes with ground glass inclusions

A

PML

56
Q

Levera —- mood swings

A

Diverting of orthography to phonology impaired

Surface alexia

57
Q

Complex hallucinations

A

Non dominant lobe

58
Q

Cranial and causal end of neural tube differentiated by molecular marker

A

Noggin

59
Q 
Normal alpha activity on EEG, which is suppressed by stimulating the patient  indicates all except
A. Locked in state 
B. Hysteria 
C. Catatonia
D. Pontine damage✅ 
ECG changes secondary to intracranial hemorrhage include all except 
A. Peaked T waves
B. Deep symmetric T waves
C. Increased QT interval
D. ST elevation✅
A 
ECG changes secondary to intracranial hemorrhage include all except 
A. Peaked T waves
B. Deep symmetric T waves
C. Increased QT interval
D. ST elevation✅
60
Q

Beta glucan D testing used for

A

aspergillosis

Candida

Blastomycosis

61
Q

Secondary Parkinsonism

Asso with LIVER FAILURE

A

DRUGS

anti HTN — CCB

anti arrythmic — AMIODARONE

62
Q

semantic memory

LATERAL TEMPORAL LOBE

Episodic memory

MEDIAL TEMPORAL LOBE

A

Procedural memory

BASAL GANGLIA CERBELLUM

working memory

PFC

63
Q

Order of involvement in extra pontine

Mylinosis

A

CLTP

CBBLM

LGB

THAL

PUTAMEN

64
Q

Hyperventilation May be helpful

Also in

A

Prinzmetal angina

Fasciculations

65
Q

Pcsk 9 inhibitors

A

Decrease lipoprotein a levels

66
Q

Causes of MND

Hyperthyroidism

Hyperlipidemia

Hyperglycinuria

A

Cu Zn deficiency

Lead aluminium

Herpes zoster

HTLV1

67
Q

Role of IVIG

A

Supersaturates the

Fc receptor of macrophages

68
Q

Childhood onset chorea

A

ADCY5

perioral movts

69
Q

Shapiro syndrome

A

agenesis of CC

Autonomic dysfunction due to limbic and Paralimbic circuits

Hyperhydrosis

70
Q

Ideational apraxia associated with
A dominant frontal lobe
B non dominant frontal lobe
C dominant parietal lobe ✅

A 
Inaccurate and approximate answers seen with
A aphemia
B ganser syndrome ✅ 
C charles bonnet syndrome 
D none
71
Q

Bacterial infection mimicking viral encephalitis

  1. listeria
  2. bartonella✅
  3. mycoplasma

Ologoclonal bands is seen in

  1. HSV
  2. HTLV✅
  3. EV71
  4. Powassan virus
A

Viral infection mimicking bacterial meningitis

  1. HSV✅
  2. EBV
  3. WNV
  4. VZV
72
Q

Bruns ataxia. NPH

Kennedy

gynecomastia with infertility
CAG repeats
Subtle sensory findings

A

Familial FTD is 10 % of FTD

73
Q

Mollaret like mono nuclear cell in CSF

seen in WNV

A

Reduced csf glucose

Mumps

Lcmv

CMV

( normal in hsv early stage )

74
Q

Meningitis in immunocomprpmised

Acanthameba

Meningitis causing SAH gnathostoma

A

Recurrent meningitis

Behcets
VKH
Mollarets

75
Q

superior colliculus involvement

A

Loss of convergence and

Pupillary reflex

76
Q

Prions PMC amplification

Centers for step generation

Midbrain
STN
Pontine tegmentum

A

FFEVF asso with BECTS

AEDS asso with BM suppresion

Valproate

Ethosuximide

77
Q

ALS mimicking PLS

A

Alsin

TBK1

78
Q

Risk of seizure after 1 st unprovoked sz in 1 year is

A

30 - 70 %

79
Q

MG other Abs

A

Netrin

Agrin

Titin

Not Desmond

80
Q

Mc genetic abnormality AML

A

NPM 1

81
Q

SLE LUNG

A

no pneumonia

Pleuritis

Alveolar hemorrhage

Pulm hypertension

82
Q

Sarcoidosis

A

Optic neuritis

Band keratopathy

Conjunctival nodule

83
Q

HIT

A

Dvt common

Platelets transfusion not required

Stop warfarin also till INR normal

Use 10 a inh instead rivoroxaban

84
Q

Causes of bouts of rec pancreatitis

A

Alcohol

Hypercalcemia

Hypertriglyceridemia

85
Q

Madras motor neuropathy

A

Deafness

Oropharyngeal weakness

86
Q

Mercury intoxication

A

Choreo athetosis

Ataxia

87
Q

PR interval prolonged

LACOSAMIDE

A

QT shortening

Rufunamide

88
Q

Gag deletion

A

DYT 1

89
Q

Kir 2.6 hyperthyroidism

A

Anderson tawil asso with KCNJ2

90
Q

Karyorrhectic debris
Cd68 positive
Lymphadenopathy

Kikuchi

A

Recurrent fevers with common infections being -ve

Sle 
Periodic fevers ( FMF and TRAPS — difference is 
FMF - ocular features present
Treatment of FMF -colchicine 
Complication of FMF -amyloidosis and ARF
91
Q

anti Xa inh are Xabans

anti thrombin

Indirect heparin warf by binding to heparin - antithrombin - thrombin complx

Direct dabigatran argatroban

A

HIT complication of heparin , thrombosis

Use direct thrombin inh instead
Dabigatran

aRgatroban

Fondaparinux

92
Q

P pulmonary
A artery
N never

A

Granulomas in these 4

Takayasu

Giant cell

Wegener

Churg strauss

93
Q

Psp Mc dystonia

bleoharospasm

A

Mc c of drop attack
With loc sz
Without TIA

94
Q

Life expectancy not altered with which myositis

A

IBM

95
Q

Kearns sayre

onset b4 20 yrs

CPEO . Pigmentary retinopathy

Gonadal dysfunction, delayed puberty

DM . Hypo PTH

A

Absence of head impulse sign with vertigo suggest central cause.

Commonly involved canal in BPPV post

Most patients with vestibular neuritis recover spontaneousl

Dose of meclizine is 25-50mg 3 times a day

96
Q

restless leg syndrome Doc

A

Ropinarole

PD - rescue drugs apo and amantadine

97
Q

Fibrinogen
Esr
Crp
Serum amyloid A

Positive acute phase reactants

A

Albumin

Transthyretin

Retinol binding protein

Negative phase reactants

98
Q

Alzheimer’s

A

Last to be affected is PFC so personality changes

HRT , NSAIDS , low SES

Mc in females

Type 3 DM is associated

99
Q

Cystatin C for GFR estimation affected by

Smoking

DM

Race

not affected by alcohol or age

A

blood grouping 9p

100
Q

Nerve biopsy diagnostic for

Vasculitis
Hansen
Amyloidosis

Not CIDP

Onion bulb — CMT refsum lead neuropathy

A

Neuromyopathy
colchicine
Also colchicine is anti inflammatiry , drunken gait of neutrophil
Chenitaxis from site of inflam

Essential tremor 4– 8 hz frequency

101
Q

B/ l facial palsy

```
sarcoidosis
GBS
Lymes
Rosenthal melkerson
fissured tongue lipswelling facial palsy
~~~

A

Obst sleep apnea

Class 3 of pulm HTN

102
Q

FTLD 3 CHMP 2B

Hiv demylenating facial nerve palsy

Hypothyroid entrapment of facial nerve in middle ear facial palsy

A

REM sleep disorder and anosmia absent in PSP

Early features of others

103
Q

Sarcoidosis
Mc organ lung

Upper lobe of lung
Egg shell calcifications ( also in silicosis )

A

Silicosis and pap

Crazy paving

Pap positive

104
Q

hodgkins poor prognosis

Age > 45

Hb < 10.5

Wbc count >15000

A

Hypocellular marrow with or without cytopenias

legionnaires disease

105
Q

Basal ganglia encephalitis

Anti dopamine 2R

Mc Keith criteria DLB

A

Icatibant for angioedemas

Mowat Wilson syndrome

Agenesis of CC
Genito ur anamalies
ZEB2 mutations

Huntington vertical gaze palsy
Also olivopontocerebellar degeneration

106
Q

Meningitis with craniotomy
gram negative bacilli

Meningitis with csf shunts
Staph / MRSA

A

Ocrelizumab is against CD20

random (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions