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random 2 Flashcards

1
Q

Abacavir hypersensitivity
HLA 5701
However slows the progression of HIV

Kaposi sarcoma lower limbs mc

Mcc of pleural effusion one AIDS -

A

Best inv for hiv is viral rna pcr
Can detect up to 40 copies / ml of blood

Hairy leukoplakia
Not premalignant
Scrapings - pseudomycelia

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2
Q

Nevirapine increases p 450 met

A

Tenofovir ARF

Zido Bm Supresn

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3
Q

Coccidial meningitis - doc flucanazole

IRIS can be fatal , usually with CD4 les than 50

A

Alcoholic liver disease
Ig A

Auto immune ig G

PBC ig M

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4
Q

Antibodies

AI hepatitis 1
ANA , AMA , pANCA , ASMA , SLA

AI hepatitis 2
LKM1 , LCA 1

AI hepatitis 3 : SLA

A

LKM1 : AI hepatitis

Lkm2 drug induced

Lkm3 : hepatitis D

LKM1 chronic hep c

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5
Q

Infarction in one dominant temporal lobe doesn’t cause deafness
As cochlear nucleus receives from both tempo lobes

Multiple small ulcers in Esophagus
HSV

A

NNRTI s are resistant in HIV 2

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6
Q

PBC

Earliest is fatigue then pruritus and hyperpigm

IgM AMA

Florid duct lesions due to granulomas

A

PSC

onion skin fibrosis

GURD criteria : fat embolism

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7
Q

Contralateral hemineglect
Spatial disorientation
Constr apraxia

Non dominant parietal lobe

A

Non verbal memory
non dominant temporal lobe

Crural monoplegia (leg one side )and ur incont A2 infarct

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8
Q

Avg TIA 12 min

CADASIL NOTCH 3

Mca m1 - mca stem
M2 Sup div- frontal and sup parietal
M2 inf div- temporal and inf parietal gerstmann

A

Anton b/l P2 segment / distal PCA

Dejerine P1

Weber penetrating branches of PCA

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9
Q

Yellow fever Torres bodies

Mc ischemic kidney zone
is medullary Thal

Least oerfused area of body
: outer medulla

A

NREM vs rem

Decreased HR , BP , CBF ,
And reduced parasymp activation

Fibrillation potentials on EMG
ALS , IBM , diabetic polyneuropathy, CTS

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10
Q

GURD criteria : fat embolism

A

Tia min time is 12 min

CADASIL notch 3

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11
Q

Subcortical U fibres involved in

PML
MS not in NMO
ADem

A

acquired pendular nystagmus — MS

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12
Q

Sodium oxybate gaba b agonist

For narcolepsy with cataplexy in pts more than 16 yrs age

A

Photograph negative pulm edema

Chronic eosinophilic pneumonia

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13
Q

Tug test

A

3metres or 10 feet

12 seconds

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14
Q

Cva

Ecg changes

Qt prolongation

Deep t wave inversions

A

Mc HDL disorder

HDL type 4

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15
Q

Amebic liver abcess and

Amebic colitis

Treatment
Metrogyl 750mg tid for 5-10 days

A

Ring enhancing

GBM

toxoplasma

Actinomycossis

Not in medulloblastoma

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16
Q

1 unit of FFP increases clotting factors by

A

3 %

17
Q

Sofa score

GCS
MAP
Pao2/ fio2
Ur output
Sr creatinine
Platelets
BR
A 
Cns 
Cvs
Rs
Renal
Hepatic 
Hemat
18
Q

Picture frame vertebra

A

Pagets

19
Q

Precocious puberty

Boys cut off 9yrs

A

Testosterone replacement
Contraindications

Breast cancer

Prostrate cancer

Pct > 50 %

20
Q

Pyridoxine is used to treat

Hyperoxaluria

A

.

21
Q

Jug foramn 9 10 11

Avelli 10
Scmidt 10 ,11
Jackson 10, 11 , 12

Sicard 9,10,11,12
Villaret above and sympathetics

A

SOF 3,4,5,6

Orbital apex SOF + 2

Petrous apex : 5,6

CP angle : 8 +/- 5/7/cbllar hemisphere

22
Q

Sarcoid has optic neuritis
Liver may involve
Cardiac involvement unlikely in sarcoid

Meningeal syphilis follows secondary syphilis

A

RA asso with some generalised osteoporosisu

Ant choroidal artery supplies
Choroid plexus
Optic tract
LGB

23
Q

Hypogammaglobulinemia

Thymoma

Myeloma

CLL

A

Hypogammaglobulinemia

Predisposes to

Cl difficile

Giardiasis

24
Q

Enterovirus implicated in Pathogenesis of sjogren a

Cd8 infiltration in sjogren

A

Caspar criteria psoariatic arthritis

25
Q

Delayed bone age

Precocious puberty

A

Hypothyroidism

26
Q

NTD elev afp

Anencephaly elev afp and low hcg

A

Downs elev HCG and low afp

27
Q

MEDNIK Syndrome

A

Copper abnormalities

28
Q

Pseudo lymphoma

A

Seen with phenytoin

29
Q

Emotion is controlled by frontal lobes

Limbic system has connections with frontal lobes
Expression of emotions is by limbic system

Amygdala feeling center of Brain

A

COAT ‘s disease

Asso with FSHD

30
Q

ADA 2 TB present in monocytes

A

In Hiv Igra

T spot preferred than. Quantiferon gold

31
Q

Infant earliest presentation of hydrocephalus is

Sutural separation or bulging fontanelle

A

Adreno nyeloneuropathy

ATAXIC paraparesis

No response to bm transpalant except cognitive improvement

32
Q

Hypoglycaemia

<30 asso with coma

A

< 10 assoc with medullary hypoglycaemia

33
Q

Alzheimer’s asso with

A

Sundowning
Worsening of dementia in the evening

Apraxia

34
Q

hypomagnesimia

Hypokalemia

hypercalcemia

A

Cause DIGOXIN TOXICITY

35
Q

Col 1 bone

Col 2 cartilage

Col 3 conn tissue ehlers marfans mvp

Col 4 basement mem

Col 8 endothelium

A

Men1

Pth mc is hyperplasia

36
Q

Death in churg Strauss

A

Cardiac

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