Random facts for heme- exam 1 Flashcards
mneumonic for ordering a D dimer and dont want it to be a false pos
CRIIP! False alarm.
Cancer, Recent Surgery, Infection, Inflammation, Pregnancy
Coombs test- what does it do and when is it false pos
detects presence of antibodies on the surface of RBCs which ultimately causes RBC destruction
-false positive if taking these medications:
Methyldopa, Levodopa, Cephalosporins, penicillin, quinidine
My Lovely Cat Purrs Quietly (for Antibodies)
Bodys most reliable indicator of iron and most accurate indicator (2)
-Ferririn (reliable & ordered often) and bone marrow (accurate & hard to order)
-both of these are better than serum iron or TIBC
What does B12 need to be absorbed
intrinic factor (req intact stomach) from the stomach + absorption in the ileum
where is folic acid and B12 stored
liver
Does folate need B12 to be absorbed into tissues or vice versa?
B12 is needed to move folate into tissue cells. Folate is absorbed in the jejunum but stays in the blood until B12 lets it into tissues.
when is transfusion indicated at 7-8 and 9-10. what about in emergency?
8-10 hgb
Anemia, bleeding, ACS
7-8 hgb
Post op, CVD
in emergency, you cant measure hgb (until 15 mins after transfusion and they cant have an active bleed)
What is contained in FFP?
How long to thaw
Contains coagulation factors, fibrinogen, antithrombin, albumin, protein C and protein S
Come Find A Crab AT Sea
24 hours, then it must be given then or it will degrade the factors
Cryoprecipitate
vWf, 8, 13, fibrinogen
White Wedding For 813
Indications for the transfusion of plaetlets
<10,000 to prevent spontaneous hemorrhage.
<50,000 who are actively bleeding, are scheduled to undergo an invasive procedure, or have a qualitative intrinsic platelet disorder.
Patients with a platelet count <100,000 who have a central nervous system injury, have multisystem trauma, or are undergoing neurosurgery
normal platelet count who have ongoing active bleeding and a reason for platelet dysfunction, such as a congenital platelet disorder, chronic aspirin therapy, or uremia