Random drugs

Question 1

What are the mast cell stabilizer drugs?

Answer 1

Cromolyn
Sodium Cromoglycate

Same thing

Question 2

Where do mast cell stabilizers work?

Answer 2

Local affect on nasal mucosa or eyes

Does not cross biological membranes well

Question 3

How do mast cell stabilizers work?

Answer 3

Inhibit PLA-induced degranulation of sensitized mast cells

Inhibits release of mediators of Type I allergic rxns–including histamine and cysteinyl leukotrienes

Question 4

What drug is an agonists for both alpha and beta receptors, and used in cases of anaphylaxis?

Answer 4

Epinephrine

Question 5

Besides affecting blood vessels, what else does epinephrine do?

Answer 5

Decongestion–inhibits adenyl cyclase

Question 6

Do pregnant/breast-feeding women need to worry about epinephrine?

Answer 6

Yes…crosses placenta and distributes into breast milk

Question 7

What eye condition is epinephrine contraindicated in?

Answer 7

Closed-angle glaucoma

Question 8

Besides anaphylaxis, when else can epinephrine be used?

Answer 8

In conjunction with local anesthetics

Question 9

What is the name of the drug that is an anti-IgE antibody?

Answer 9

Omalizumab

Question 10

When is omalizumab used?

Answer 10

Patients with allergic asthma that is resistant to inhaled steroids and long-acting beta-2 agonists