Random Flashcards

1
Q

MND presentation

A

Upper and lower MN signs

no sensory involvement

Bulbar signs - tongue wasting, fasciculations

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2
Q

Hemisection of cord

A

Ipsilateral paralysis + loss of light touch/vibration

Contralateral loss of pain + temp

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3
Q

Cluster headache

A

More common in men
Unilateral, autonomic features
Px feel the need to move around

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4
Q

Amaurosis fugax

A

Curtain drawing over eyes

retinal a. embolism as a consequence of AF

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5
Q

Status epilepticus tx

A

Rectal diazepam -> intravenous lorazepam

No response? load urgently with phenytoin

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6
Q

Complex partial seizure

A

They don’t remember having it

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7
Q

Psoriasis nail changes

A

Onycholysis

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8
Q

Basal cell carcinoma main characteristic

A

Rolled edge

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9
Q

Squamous cell carcinoma characteristics

A

Hyperkeratonic, ulcerated nodules with inverted edges

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10
Q

Breslows thickness

A

Assesses the invasion of the melanoma starting from the granular layer of the epidermis to the deepest part

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11
Q

Negative D-dimer?

A

Pulmonary embolism

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12
Q

Genetics in burkitts lymphoma

A

t (8,14)

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13
Q

Rouleaux formation

A

Seen in multiple myeloma

RBC’s adhere and stack on each other

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14
Q

LSE anaemia?

A

Normocytic normochromic due to decreased erythropoeisis

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15
Q

Mccune albright syndrome

A

genetic disorder causing uncontrolled secretion of a number of endocrine glands

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16
Q

De quervains thyroiditis

A

transient change in thyroid status due to a viral infection

17
Q

Anion gap formula

A

(Na + K) - (Cl + HCO3)

18
Q

Familial gastric cancer mutation?

A

CDH1 (e-cadherin) mutation

19
Q

Hepatocellular carcinoma marker

A

Alpha feto protein

20
Q

Cirrhosis LFT findings and consequences

A

Rasied bilirubin and PT, lowered albumin and platelets

Ascites, encephalopathy, variceal bleeding, hepatocellular carcinoma

21
Q

Spontaneous bacterial peritonitis?

A

Ascitic tap >250 neutrophils

IV antibiotics and albumin

22
Q

Causes of dysphagia

A

Oesophageal carcinoma, oesophageal ring, peptic strictures, retrosternal goitre

23
Q

Difference between duodenal and gastric ulcer pain?

A

Duodenal pain normally relieved after meals, gastric worse.

24
Q

Oesophageal varices tx

A

B blockers

TIPPS 2nd line

25
Q

Conditions predisposing to colorectal cancer

A

IBD, lynch syndrome

26
Q

2 commonest causes of acute pancreatitis?

A

Alcohol, gallstones

27
Q

Tx for massive haematemesis?

A

Fluid resusc

Terlipressin

Antibiotics

28
Q

Goldstandard inv for suspected colorectal cancer?

A

Colonoscopy - permits biopsies + localisation of the tumour

29
Q

Hereditary haemochromatosis initial tx

A

Venesection

30
Q

Mallory weiss syndrome?

A

Oesophageal laceration. Forceful prolonged vomiting and haemetemesis

31
Q

Hereditary nephritis, sensorineural deafness and occular abnormalities point to what?

A

Alport syndrome - genetic defect in type IV collagen

32
Q

Wolfram syndrome?

A

Can cause DI, DM, optic atrophy and deafness

Glucose would be detected on urine dipstick

33
Q

Most common sx of bladder cancer?

A

Painless haematuria with weight loss

34
Q

What are abdominal bruits highly suggestive of in renal?

A

Renovascular disease