Random 6 - own notes Flashcards

1
Q

Antiemetic to avoid in prolonged QTc?

A

Ondansetron - 5HT3 antagonist

Instead use Cyclizine (H1 antagonist)

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2
Q

Dose of dexamethasone in croup?

A

0.15mg/kg

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3
Q

Cause of lose stools in someone treated for osteoporosis?

A

Alendronic acid AND PPI can cause loose stools

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4
Q

Analgesic causing ankle oedema?

A

Naproxen

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5
Q

Length and type of treatment for thrush in pregnancy?

A

LONGER than the usual and topical or pessary only e.g. clotrimazole pessary 100mg PV OD for 7 days (BNF for usual dose says 100 mg for 6 night)

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6
Q

Acute pain in shingles treatment?

A

Paracetamol

NB: amitriptyline is used for the postherpetic neuralgia.

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7
Q

How is loperamide taken?

A

After each loose bowel movement (minor SE: causes fatigue)

NB: this information is usually written alongside the dose and indication

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8
Q

What important information should you tell a patient about ciclosporin?

A

Will need to have renal function monitoring

NB: in questions with pregnancy SE options, only choose these if the patient is of child bearing age.

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9
Q

88kg patient needs 50mg/kg acetylcysteine added to 500ml of 5% dextrose. Acetylcysteine is available in 10ml ampoules of 200mg/ml. What rate will the drug be given over 4hrs?

A

88 x 50 = 4400 required
4400mg = 22ml
22ml + 500ml = 522ml
522/4 = 130.5ml/hr

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10
Q

How much potassium in a 500ml bag of 0.9% saline with 0.15% K?

A

10mmol

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11
Q

Dangerous side effect of GLP1? Most common SE?

A

Pancreatitis
Most common: vomiting

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12
Q

Treatment of haloperidol induced parkinsons?

A

Drug induced parkinsonism is treated with PROCYCLIDINE (anti-cholinergic) not Levodopa.

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13
Q

What BP should you stop COCP?

A

160/95

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14
Q

What level of dose of azathioprine if TPMT activity is low?

A

Low dose to reduce toxicity

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15
Q

Opioid toxicity caused by m/r morphine. What drug do you switch to?

A

Oxycodone - metabolised by the liver to inactive metabolites

NB: morphine is also metabolised by the liver but releases an active metabolite called morphine-6-glucuronide which is renally excreted and can acummulate.

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16
Q

Thyrotoxicosis with amiodarone treatment. What do you do?

A

Stop amiodarone - to achieve control at least temporarily