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Haematology Year 2 > Random > Flashcards

Random Flashcards

1
Q

what does back pain, hypercalcaemia, renal failure suggest?

A

multiple myeloma

BENCE JONES proteins

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2
Q

what is used to treat warm autoimmune haemolytic anaemia?

A

steroids - prednisolone

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3
Q

what is used to treat cold autoimmune haemolytic anaemia?

A

supportive - keep patient warm and if required transfuse blood using a blood warmer

steroids have no role

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4
Q

what can myelodysplasia progress to?

A

acute myeloid leukaemia

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5
Q

what is the target of rituximab?

A

CD20

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6
Q

what is the target of imatinib?

A

BCR ABL1 tyrosine kinase (CML)

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7
Q

what do smear cells suggest?

A

CLL (chronic lymphocytic leukaemia)

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8
Q

which technique is used to clarify the lineage involved in leukaemia?

A

immunophenotyping

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9
Q

what is myelodysplasia?

A

acquired DNA mutation in haematopoietic stem cells

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10
Q

what are Aeur rods found in?

A

Acute myeloid leukaemia

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11
Q

what are Reed sternberg cells found in?

A

Hodgkins lymphoma

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12
Q

most common childhood leukaemia?

A

acute lymphoblastic leukaemia

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13
Q

Leukoerythroblastic film appearances is seen in what?

A

idiopathic myelofibrosis

more likely reactive e.g. sepsis, or in bone marrow infiltration

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14
Q

what are Teardrop-shaped RBCs in peripheral blood seen in?

A

idiopathic myelofibrosis

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15
Q

management for polycythaemia vera?

A

venesect until haematocrit <0.45
aspirin
hydroxycarbamide

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16
Q

what is extramedullary haematopoiesis observed in?

A

idiopathic myelofibrosis

hence can have hepatosplenomegaly

17
Q

leukaemia associated with Down syndrome?

A

acute lymphoblastic leukaemia

18
Q

congo red with apple green birefringence under polarised light?

A

amyloid

19
Q

technique to investigate cell lineage?

A

immunophenotyping

20
Q

what can myeloproliferative disorders evolve into?

A

acute myeloid leukaemia (AML)

21
Q

fava beans?

A

G6DP deficiency

22
Q

which drugs have cardiac side effects?

A

anthracyclines
e.g. doxorubicin

Haematology Year 2 (4 decks)

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