Leukaemia Flashcards

1
Q

who is AML mc in?

A

elderly

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2
Q

auer rods is seen in?

A

AML

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3
Q

which agent is used in CML?

A

imatinib

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4
Q

BCRABL+ve?

A

CML

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5
Q

smudge cells?

A

CLL

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6
Q

mc in children?

A

ALL

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7
Q

CNS infiltration?

A

ALL

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8
Q

which drugs can be used for neutropenia?

A

piperacillin/ tazobactam

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9
Q

13q deletion/ trisomy 12?

A

CLL

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10
Q

mc leukaemia?

A

CLL

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11
Q

warm haemolytic anaemia?

A

CLL

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12
Q

Richter’s transformation?

A

CLL

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13
Q

chronic, accelerated, blast phase?

A

CML

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14
Q

> ____ % blast cells?

A

greater than 20%

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15
Q

philadephia chromosome?

A

CML
(can be in AML)

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16
Q

gout?

A

CML

17
Q

gum hypertrophy?

A

AML

18
Q

what does imatinib do?

A

tyrosine kinase inhibitor
(this activity is induced by philadelphia chromosome)
BCR-ABL fusion protein drives uncontrolled proliferation & survival of myeloid cells

19
Q
A