Raine Flashcards
What was Raines aim?
To show that the bargains of murderers who pleaded not guilty by reason of insanity were different from brains of non murderers.
What was Raines hypothesis?
That seriously violent individuals would have relatively localised brain dysfunction in areas such as the:
Pre frontal cortex
Amygdala
Thalamus
Who were the participants?
41 murderers pleasing not guilty by reason of insanity (39 men 2 women)
41 matched control group (none had committed a murder)
Both groups had 6 schizophrenics
All referred to the university of California Irvine imaging centre
What was the independent variable?
Whether the participant is an NGRI to murderers or a non-murderers in the control group.
Where were the dependent variables?
-relative glucose levels in the pre frontal cortex.
-other lobes of the brain.
-amygdala, hippocampus, thalamus, medico-temporal lobe.
Was this a natural experiment?
Yes because the IV is naturally varying and the controls were matched on age and sex.
What were the experimental controls?
-All offenders were in custody and were kept medication free for two weeks.
-The control group were matched with participants in great detail.
Materials involved
-Thermoplastic head holder-individually modelled to hold subjects head. Improves images and increases reliability.
-PET scanner-image brain functioning, colour map of brain activity is generated by machine
-FDG-tracer injected intravenously to trace brain metabolism
What was the step by step procedure?
1) 10 minutes before FDG injection, participants were given practice CPT test for best ability.
2)30 seconds before injection the real task started so initial task novelty would not be recorded.
3) monitored for 32 minutes and were scanned in PET scanners.
4)brains were scanned 10 times at 10mm intervals. (To pick up differences in glucose metabolism in cerebral cortex and sub-cortical layers)
5)brain regions were identified using two techniques
Cortical peer technique (lateral areas) box technique (medial areas)
What were the overall results of the task?
There was no significant difference in the task performance between the two groups.
Evidence of significant difference in brain metabolism of glucose in a number of areas
What were the results for the frontal lobes?
Reduced glucose metabolism relative to controls in both lateral (left,right) and media (middle) pre-frontal cortical areas.
What were the results in the parietal lobes?
Had lower glucose metabolism meaning they were less aware of what they were doing.
Wha was the results for them corpus callosum?
Had lower glucose metabolism therefore harder to make decisions.
What were the results in the limbic system (amygdala)?
There were abnormalities- reduced metabolism in the left but greater in the right.v
Makes it harder for murderers to manage emotions.
What was the overall conclusion?
Brains of murderers pleading NGRI are different to non-murderers.