Ragsdale Cerveau Flashcards
Tetrodoxin
Puffer fish : blocks NA+ channels
Batrachotoxin
Phyllobates frogs: Na+ channels activator (deadliest poison) ( pcq des que 1% des channels ouverts, tout ouvre)
Myelin is formed by
PNS: Schwann cells or neurolemmocytes
CNS: oligodendrocytes
Saltatory conduction
Quand il y a de la myelin
Main excitatory neurotransmetteur in the brain
Glutamate
LTP
Long-term potentiation
Main inhibitory neurotransmitter in the brain:
GABA
Origin of neurons that release neuromodulators
Small brainstem or midbrain nuclei
Un Bb muscle fiber
Myoblast
Single unit of contraction
Sarcomere
Entre les thick and thin filaments
Crossbridges: head groups of the myosin molecules
NT at neuromuscular junction
Acetylcholine
Muscle contraction: 2 Ca channels
DHP receptor (direct link with T-tubules: extra cellular fluid) Ryanodine receptor (flow of Ca comes from SR: sarcoplasmic reticulum)
How does Ca triggers contraction?
Binds to trop on in on thin filaments. Triggers a conformational change that makes the tropomyosin moves from the myosin binding site on the thin filaments
Première source d’ATP dans le muscle en contraction
Transfert du phosphate de Creatine Phosphate à de l’ADP (donc on obtient ATP et Creatine) faite par Creatine Kinase