Radiopharmaceuticals ☢

Question 1

What is
Imaging radiopharmaceuticals

Answer 1

Often GAMMA

low doses

Illicit no oharmacological response, and induce no side effects

Question 2

What is
Therapy radiopharmaceuticals

Answer 2

ALPHA, BETA, GAMMA

absorbed at the local tissue at side for effect

Question 3

Radiation dose:

Distance -

Answer 3

Dose recieved is proportional to the inverse square of the distance

Dose = 1/ distance^2

Question 4

Radiation dose:

Time…

Answer 4

Dose recieved is directly proportional to time of exposure

Dose = time

Question 5

Technetium 99m
Decays via…. ?

Answer 5

Gamma emmission, half life of 66 hours

Question 6

How to make Mo-99?

Answer 6

Hitting target (Uranium-225) with neurons, undergoes nuclear fusion into

= MoO4/2-

Question 7

Mo99 coverts to what every 66hours?

Answer 7

TeO

Question 8

Specific activity

Question 9

Which scans is Fluoride 18 ideal for?

Answer 9

PET scans

Question 10

Which radioisotopes do SPECT scans use?

Answer 10

Uses gamma emitting radioisotopes
(Tc-99m..)

Question 11

How does FDG [F18] work?

Answer 11

1. FDG gets in cell
2. Phosphorylated version gets trapped inside the cell