Radiochemistry Flashcards

1
Q

What are isotopes?

A

Atoms that have the same number of protons but different number of neutrons in their nuclei.

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2
Q

What are radioisotopes?

A

Isotopes that are radioactive. They have unstable atomic nuclei and lose energy by emitting radiation.

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3
Q

What radioisotopes emit radiation as alpha particles?

A

Isotopes with an atomic number of 60 or higher.

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4
Q

What radioisotopes emit radiation as beta particles?

A

Isotopes with excess neutrons.

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5
Q

What is decay often accompanied by?

A

The emission of electromagnetic radiation such as gamma or x-ray.

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6
Q

What is the difference between an alpha and beta particle?

A

An alpha particle is a helium nucleus (two protons and two neutrons) whereas a beta particle is a fast moving electron.

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7
Q

What are the key properties of alpha particles?

A

Slow-moving, small range in air (3cm), no external hazard but contamination can be very serious.

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8
Q

What are the key features of beta particles?

A

A variable energy, a 1m range in air, have an external and contamination hazard.

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9
Q

What are they key features of gamma particles and x-ray particles?

A

A long rang and have an external hazard.

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10
Q

What is a half life?

A

The time taken for half a radioactive material to become stable.

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11
Q

What is the inverse square law?

A

The idea that the energy of radiation decreases in proportion to the square of the distance from its source.

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12
Q

What regulations surround the use of radioactive substances?

A

The radioactive substances act and the ionising radiations regulations.

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13
Q

What safety precautions must be taken?

A

Sufficient training (knowledge, planning and preparation), shielding, distance, reduced exposture time and always working together.

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14
Q

What are the major isotopes used in the life sciences?

A

Phosphorus-32, sulfur-35, tritium (3H0 and iodine-125.

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15
Q

What is the half life of phosphorus 32?

A

14.3 days.

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16
Q

What is the range in air of phosphorus 32?

A

790cm.

17
Q

What is sufficient shielding for phosphorus 32 and sulfur 35?

A

1cm perspex.

18
Q

What are some of the uses of phosphorus 32?

A

Labelling nucleic acids such as in DNA fingerprinting.

19
Q

What is the half life of sulfur-35?

A

87.4 days.

20
Q

What is the range of sulfur 35?

A

26cm in air.

21
Q

What are the uses of sulfur 35?

A

Labelling proteins and DNA sequencing.

22
Q

What is the half life of tritium?

A

12.4 years

23
Q

What is the radiation of tritium, phosphorus 32 and sulfur 35?

A

Beta.

24
Q

What is the range of tritium?

A

6mm in air.

25
Q

What shielding is required for tritium??

A

None.

26
Q

What are the uses of tritium?

A

Labelling sugars and amino acids.

27
Q

What is the half life of iodine 125?

A

59.6 days.

28
Q

What is the radiation of iodine 125?

A

Gamma, x-rays.

29
Q

What is the shielding required for iodine 125?

A

Lead.

30
Q

What are the uses for iodine 125?

A

Labelling peptides.