RA When to Use

Question 1

Corticosteroids

Answer 1

Used for anti-inflammatory and immunosuppressive properties

Question 2

DMARDs

Answer 2

Potential to decrease/prevent joint damage & preserve joint integrity

Question 3

DMARD examples

Answer 3

MTX

Sulfasalazine

Hydroxychloroquine (HCQ)

Question 4

Adalimumab (Humira)

Answer 4

Patients who have inadequate response to one or more DMARDS

Question 5

Golimumab (Simponi)

Answer 5

Moderate to severe RA

Question 6

Certolizumab (Cimzia)

Answer 6

RA patients with moderate to severe disease

Question 7

Abatacept (Orencia)

Answer 7

Moderate to severe RA

If had inadequate response to one or more DMARDs

Question 8

Tocilizumab (Actrema)

Answer 8

Moderate to severe RA after inadequate response to one or more DMARDs

Question 9

Sarilumab (Kevzara)

Answer 9

Moderate to severe RA after inadequate response to one or more DMARDs

Question 10

Rituximab (Rituxan)

Answer 10

For moderate to severe RA

In those with inadequate response to TNF antagonists

Question 11

Tofacitinib (Xeljanz & Xeljanz XR)

Answer 11

Moderate to severe RA after inadequate response to MTX

Question 12

Baricitinib (Olumiant)

Answer 12

Moderate to severe RA after inadequate response to TNF

Question 13

Upadacitinib (Rinvoq)

Answer 13

Moderate to severe RA after inadequate response to MTX

Question 14

Anakinra (Kineret)

Answer 14

IL inhibitor / BRM / bDMARD

Used when TNFi fails

Used w/ MTX