R and S configs

Question 1

Absolute Configuration Def

Answer 1

The exact spatial arrangement of atoms in a chiral molecule

Question 2

Rules for assigning priority of substituents

Answer 2

The higher the mass no of an atom = higher the number assigned (biggest = first, if there are 2 of equal value, move onto next closest atom) and the more bonds between two atoms = higher priorities (ie triple > single)

Question 3

R enantiomers Outline

Answer 3

Atoms undergo clockwise rotation

Question 4

S enantiomers Outline

Answer 4

Atoms undergo anticlockwise rotation

Question 5

Why do enantiomers undergo rotation

Answer 5

Put substituent of lowest priority furthest away from us

Question 6

Rule of double switch

Answer 6

lowest priority atom must be at furthest point. there must be 2 times (or a multiple) that a group must be switched

Question 7

Fischer Projection Outline

Answer 7

Horizontal = 2 substituents coming towards you. Vertical = 2 substituents going away from you. Used when there is more then 1 chiral carbon

Question 8

Eudismic Ratio Calc

Answer 8

(Activity of more active enantiomer) / (activity of less active enantiomer)