Quizes Flashcards

1
Q

Typical lab results typically seen in lymphoid chronic thyroiditis are:
a.Decreased TSH, increased T4 and T3, anti-TPO antibodies absent
b.Increased TSH and T4, decreased T3, anti-TPO antibodies present
c.Increased TSH, decreased T3 and T4, anti-TPO antibodies present
d.Increased TSH, decreased T3, and T4, anti-TPO antibodies absent

A

c. Increased TSH, decreased T3 and T4, anti-TPO antibodies present

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2
Q

Which type of cells are responsible for initiating the immune response to islet cells in Type 1 Diabetes
CD4+ T cells
CD8+ T cells
B cells
Macrophages

A

CD4+ T cells

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3
Q

Autoimmune hepatitis is most common in:
Young men
Older men
Young women
Alcoholics

A

Young women

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4
Q

B cells undergo a second process of selection during their maturation.
True
False

A

True

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5
Q

The thyroid is responsible for deleting autoreactive T cells that have the potential to cause autoimmune disease.
True
False

A

False

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6
Q

One of the most frequent causes of drug-induced lupus is:
Chloramphenicol
Procainamide hydrochloride
Isoniazid
Penicillin

A

Procainamide hydrochloride

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7
Q

SLE is more common in:
Male infants
Female infants
Adolescent through middle-aged women
Adolescent through middle-aged men

A

Adolescent through middle-aged women

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8
Q

Patients with SLE typically manifest:
Butterfly rash over the bridge of the nose
Skin lesions on the arms and legs
Ulcerations on the trunk
Photophobia

A

Butterfly rash over the bridge of the nose

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9
Q

Rheumatoid arthritis is known to be caused by genetic issues.
True
False

A

False

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10
Q

Arrange the steps of pathogenesis of rheumatoid arthritis is the correct order.
Initiation of synovitis by the primary causative factor
Subsequent immunologic events that perpetuate the initial inflammatory reaction
Transition of an inflammatory reaction in the synovium to a proliferative, destructive tissue process

A

Initiation of synovitis by the primary causative factor

Subsequent immunologic events that perpetuate the initial inflammatory reaction

Transition of an inflammatory reaction in the synovium to a proliferative, destructive tissue process

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11
Q

Which is the least common of the major immunoglobulin classes of rheumatoid factor.
IgA
IgG
IgM

A

IgA

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12
Q

What is the most frequent cause of death in a patient with multiple myeloma?
Skeletal distruction
Chronic renal failure
Neurologic disorders
Infectious diseases

A

Infectious diseases

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13
Q

Cryoglobulins are proteins that precipitate or gel at:
-18oC
-4oC
0oC
4oC

A

0oC

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14
Q

Most patients with multiple myeloma manifest:
Bone pain
Acute renal failure
No symptoms
Hepatomegaly and splenomegaly

A

Bone pain

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15
Q

Patients with Waldenstrom macroglobulinemia exhibit abnormally large amounts of:
IgM
IgG
IgE
IgA

A

IgM

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16
Q

Light chain disease represents about ________ of monoclonal gammopathies.
5-10%
10-15%
15-25%
25-50%

A

10-15%

17
Q

MGUS is characterized by all of the following except:
Less than 10% plasma cells in the bone marrow
Presence of lytic bone lesions
Anemia
Hypercalcemia

A

Presence of lytic bone lesions