Quiz 7--Equine & Ruminant Anesthesia Flashcards
Two antibiotics that can have bad interactions with anesthetics
Aminoglycosides (profound weakness by altering Ca release)
K-Penicillin
Concerning horse anesthesia:
1) what should be withheld before surgery
2) for how long
1) just food (not water)
2) for 12 hours (longer may prolong recovery)
Most commonly used opioid analgesic in horses
Butorphanol
What two types of drugs are combined with a neuroleptanalgesic
sedative/tranquilizer with an opioid
A good drug combination for separation anxiety in mares
Ace + Xylazine
Drug combinations including ____ wouldn’t be ideal for CT because?
Butorphanol; it enhances hearing so horses may become anxious
Which sedative, when combined with butorphanol, induces LESS ataxia
Detomidine (compared to Xylazine)
Which neuroleptanaglesic drug combination can also be given as a CRI?
Detomidine + Butorphanol
3 main effects of Lidocaine
Analgesic
Prokinetic
Anti-inflammatory/anti-endotoxic
Which drug is commonly used as adjuctive treatment for sepsis and endotoxemia in horses?
Lidocaine
How does Lidocaine cause analgesic effects?
Na channel blockade
this is why it’s good for arrhythmias too
On which receptor does Ketamine act to produce its anesthetic/analgesic effects
NMDA (antagonist)
Typical rate for a Ketamine CRI
0.4-0.8 mg/kg/hr
Name antagonists for:
1) alpha-2 antagonism (3)
2) Opioids (1)
3) Benzodiazepines (1)
1) yohimbine, Tolazoline, Atipamezole
2) Naloxone
3) Flumazenil
Unless contraindicated, EVERY horse receives what as part of their anesthetic protocol?
pre-medication
A sign of overdose with GG (Guaifenesin) is?
extensor rigidity
GG is prepared as a ___% solution; and higher would cause?
5-10% (in dextrose)
Higher than 10% leads to hemolysis
Dosing for inducing with Xylazine-Ketamine in horses?
How does it change for ponies and high-strung horses?
0.5mg/lb Xylazine
1mg/lb Ketamine
increase Ketamine to 1.25mg/lb for ponies/high strung horses
Which two drugs can be added to the XK protocol in horses? Function of each?
Butorphanol–improves analgesia
Dizepam–improves muscle relaxation
What is the concentration of equine triple-drip?
0.5mg/ml Xylazine
2mg/ml Ketamine
50mg/ml GG
What is the maintenance rate for equine triple drip?
1ml/lb/hr (0.004 drops/lb/sec)