Quiz 7 Flashcards

Question 1

Q

pravastatin

Answer

A

Pravachol

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don’t take with Alcohol
Lipid levels should be take 4 weeks after initial therapy
stop before major surgery

Question 2

Q

rosuvastatin

Answer

A

Crestor

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
ADR: Arthralgia
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don't take with Alcohol
can be taken with or without meals
report s/s of jaundice or rhabdomyolysis

Question 3

Q

colesevelam

Answer

A

Welchol

hypolipidemic, bile acid sequestrant
Pregnancy category: B
Contraindications: history of bowel obstruction, hyperTG induced pancreatitis,
TG >500
empty powder into glass of water, stir well
take with meal
can be given with HMG-CoaA reductase inhibitor

Question 4

Q

atorvastatin

Answer

A

Lipitor

HMG-CoaA reductase inhibitor
Pregnancy category X
Interacts with a lot of drugs
ADR: Arthralgia. Diarrhea, HA
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes
Don’t take with Alcohol, or grapefruit juice

Question 5

Q

gemfibrozil

Answer

A

Lopid

Antihyperlipidemic
pregnancy category: C
contraindications: HSR, gall bladder disease, sever renal/ hepatic dysfxn, concurrent repiglinide
ADR: indigestion
report s/s of jaundice or rhabdomyolysis or renal failure

Question 6

Q

fenofibrate

Answer

A

Lofibra

Antihyperlipidemic
pregnancy category: C
contraindications: HSR, gall bladder disease, sever renal/ hepatic dysfxn, nursing mothers
ADR: Hyperhomocysteinemia
take with food depending on dosage form
take 1 hour before or 4-6 hours after bile acid binding resins
don’t crush or chew extended release products
products are not interchangeable

Question 7

Q

niacin

Answer

A

Niaspan

Antihyperlipidemic
pregnancy category: C
contraindications: HSR
ADR: Flushing
DI: ezetimibe, cholestyramine, colestipol,HMG-CoaA reductase inhibitor
Start with low dose and titrate up
don’t take with alcohol and warm beverages
if d/c may have to start with low dose again
aspirin or NSAIDs may reduce flushing if taken 30 mins before

Question 8

Q

simvastatin

Answer

A

Zocor

HMG-CoaA reductase inhibitor
Pregnancy category X
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes, Azole antifungals, macrolides, HIV protease inhibitors, nefazodone
Don’t take with Alcohol, or grapefruit juice
Contact prescriber before starting any new drug therapy

Question 9

Q

omega-3-acid ethyl esters

Answer

A

Lovaza

Antihyperlipidemic
pregnancy category: C
contraindications: HSR
swallow capsule whole- if you can’t swallow, puncture hole into capsule and squeeze into glass or porcelain cup
Take with food
seek medical attention if: SOB, rash, chest pain or heart palpitations occur

Question 10

Q

lovastatin

Answer

A

Altoprev

HMG-CoaA reductase inhibitor
Pregnancy category X
Contraindications: HSR, acute liver Dx, Pregnancy, elevated liver enzymes, HIV protease inhibitors
Don’t take with Alcohol, or grapefruit juice
immediate release- take with evening meal
extended release- don’t crush or cut
report s/s of jaundice or rhabdomyolysis or renal failure
Contact prescriber before starting any new drug therapy including herbal drugs

Question 11

Q

ezetimibe

Answer

A

Zetia

Antihyperlipidemic, cholesterol absorption inhibitor
Pregnancy category: C
Contraindications: HSR, gall bladder disease, severe renal/hepatic dysfxn, with statins/ pregnancy
take with or without food
can be given with HMG-CoaA reductase inhibitor
take 2 hours before or 4 hours after bile acid sequestrant

Question 12

Q