Quiz #3 WBC

Question 1

WBC Myeloid line:

Answer 1

G - Neutrophils, Eosinophils, Basophils

A - Monocytes

Question 2

WBC Lymphoid line:

Answer 2

Lymphocytes (A)

Question 3

Most abundant WBC:

Answer 3

Neutrophils - 55-70%

Phagocytes - moves toward infection

Hypersegmented in folate & B12 deficiencies

Question 4

Band Cell:

Answer 4

Increased with bacterial infections (> 10%)

“Left shift”

Question 5

RBC differential, Heinz bodies:

Answer 5

▪ Oxidized hemoglobin

▪ G6PD deficiency

Question 6

RBC differential, Howell Jolly bodies:

Answer 6

▪ DNA fragments

▪ Megaloblastic anemia, asplenia

Question 7

RBC differential, Basophilic stippling:

Answer 7

▪ Precipitated ribosomes

▪ Lead poisoning, hemolytic
anemia, thalassemia

Question 8

RBC differential,

Answer 8

Pappenheimer bodies

▪ Iron containing granules

▪ Sideroblasticanemia, asplenia

Question 9

RBC differential, Rouleaux:

Answer 9

coil of RBCs

Question 10

Absolute Neutrophil Count:

Answer 10

Actual number of neutrophils

ANC = (%neutrophils + %bands) x (WBC) / 100

2,500 – 8,000 / mm3

Question 11

Hypersegmented neutrophil:

Answer 11

Folate & Vit B 12 deficiency

Question 12

Dohle Bodies:

Answer 12

Infection, burns aplastic anemia

Question 13

Auer Rods:

Answer 13

Acute Myelogenous Leukemia

Question 14

Leukocytosis:

Answer 14

Infection

Malignancy – leukemia (increased number of abnormal WBC)

Question 15

Leukemia, myeloid line:

Answer 15

Acute (AML) and Chronic (CML)

Question 16

Leukemia, lymphoid line:

Answer 16

Acute (ALL) and Chronic (CLL)

Question 17

Chronic Myelogenous Leukemia (CML):

Answer 17

Lab: + Philadelphia
chromosome (translocationof chromosomes 9 & 22)

WBC usually > 50K

Question 18

Lymphoma:

Answer 18

Abnormal lymphocytes from lymphoid tissue

Non-Hodgkin Lymphoma - Burkitt’s lymphoma

Hodgkin lymphoma: EBV
Lab: Reed-Sternberg cell

Question 19

Platelet clumping:

Answer 19

Not mixing EDTA tube

Improper tube draw

Question 20

Giant platelets:

Answer 20

Often due to genetic conditions

Question 21

Thrombocytosis:

Answer 21

§ Infection, Inflammation, IDA

§ Essential thrombocytosis

§ Polycythemia vera

Question 22

Thrombocytopenia:

Answer 22

Immune thrombocytopenia

HELLP

Question 23

Pancytopenia:

Answer 23

Bone marrow deficiency of all 3 cell types (pancytopenia)

Question 24

Bone marrow biopsy indications (in Posterior superior iliac spine):

Answer 24

Evaluate abnormal cell
counts

Diagnose malignancy

Document abnormal iron stores