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M&R > Quiz 3 Pharmacology > Flashcards

Quiz 3 Pharmacology Flashcards

1
Q

Which 2 drugs can be used to treat hypercortisolism by inhibiting 11b-hydroxylase and 17a-hydroxylase?

A
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2
Q

Which drug is used to treat hypercortisolism by antagonizing the gluccocorticoid and progesterone receptors?

A
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3
Q

Which drugs can be used to decrease cortisol synthesis by inhibiting 11b-hydroxylase?

A
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4
Q

Which diabetes medications include a risk for hypoglycemia?

A

Insulin
Sulfonylureas
Meglitinides

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5
Q

Which diabetes medications have established CV benefits?

A

GLP-1 RAs
SGLT-2 inhibitors

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6
Q

Which diabetes medications have potential CV benefits?

A

Biguanides (metformin)
Thiazolidinediones

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7
Q

What is the MoA (effects) of metformin? What are notable side effects?

A
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8
Q

What is the MoA of sulfonylureas? What are notable side effects?

A
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9
Q

What is the MoA of thiazolidinediones? What are notable side effects?

A
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10
Q

Which diabetes medications have an FDA black box warning for risk of congestive heart failure?

A

Pioglitazone
Rosiglitazone

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11
Q

What is the MoA of GLP-1 RAs? What are notable side effects?

A
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12
Q

Which diabetes medications have an FDA black box warning of risk for thyroid C-cell tumors?

A

Liraglutide
Dulaglutide
Albiglutide
Exenatide
Semaglutaide

*All GLP-1 RAs except for Lixisenatide

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13
Q

What is the MoA of DPP-4 inhibitors? What are notable side effects?

A
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14
Q

What is the MoA of SGLT-2 inhibitors? What are notable side effects?

A
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15
Q

Which diabetes medication has a black box warning for risk of amputation?

A

Canagliflozin

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16
Q

What is the MoA of insulin? What are notable side effects?

A
17
Q

What is the MoA of a-glucosidase inhibitors? What are notable side effects?

A
18
Q

What is the MoA of meglitinides? What are notable side effects?

A
19
Q

What is the name, indication, MoA and adverse effects for the growth hormone agonist used in clinical treatment?

A
20
Q

What are the 3 somatostatin analogs used in clinical treatment? What is their indication, MoA and adverse effects?

A
21
Q

What is the indication, MoA and adverse events associated with Pegvisomant?

A
22
Q
A

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