Quiz 3 Flashcards
Dementia is characterized by acquired, persistent impairment of multiple cognitive domains that significantly alters _______, social interaction, occupational function, and the ability to perform ______ activities of daily living.
communication; instrumental
What is the preclinical condition that may suggest a person is at risk for developing dementia?
Mild cognitive impairment (MCI)
Mild cognitive impairment is a ______ stage or condition of intermediate symptoms b/w the cognitive changes associated with healthy aging and the salient cognitive impairments seen in Alzheimer’s disease or other dementias.
transition
What are the two types of mild cognitive impairment?
Amnestic MCI
Non-amnestic MCI
What type of MCI affects memory only?
amnestic
Other cognitive functions are initially affected (e.g., language or executive function) is what type of MCI?
non-amnestic
What is the diagnostic criteria for MCI?
- Self-report of memory problems
- measurable memory impairment on standardized test
- No impairments in reasoning, general thinking skills, or ability to perform activities of daily living.
List the 4 types of dementia.
Alzheimer’s Disease
Vascular Dementia
Dementia with Lewy Bodies
Frontotemporal Dementia
Episodic memory deficits
Working memory deficits
Attention and executive function impairments
language and communication impairments
Are all the earliest symptoms of what type of dementia?
Alzheimer’s disease (AD)
List some modifiable risk factors of AD
diet, exercise, controlled cardiovascular risk
List some NON-modifiable risk factors of AD
older age, positive family history, carrier status for the e4 allele of APOE gene
What language and communication aspects are affected earliest in AD?
lexical retrieval
discourse
What abilities are spared in early dementia?
Orientation to self and to other persons Semantic memory Ability to produce fluent sentences Engage in conversation Frequently follow 2-step to 3-step commands
These are all abilities in what stage of AD?
ability to follow 1-2 step commands
can sustain attention for some time
can make relevant on topic statements or comments about tangible stimuli during conversation
middle-stage
What abilities are present in later-stage AD?
attend to pleasant stimuli (e.g., music, sensory stimulation) for brief periods of time
Vascular dementia is most commonly caused by ischemic or hemorrhagic cerebrovascular disease, ________ disease, or _______ disturbances that damage brain areas vital for cognitive function
cardiovascular; circulatory
What are risk factors associated with vascular dementia?
hypertension hypercholesterolemia (high cholesterol) Type II diabetes mellitus prior history of stroke smoking
Vascular is the _____ most common cause of dementia. (first, second, third)
second
Which type of dementia is related to Parkinson’s Disease? (most commonly diagnosed after age 65)
Dementia with Lewy Bodies (DLB)
What are Lewy Bodies?
abnormal clumps of alpha-synuclein protein
When motor deficits precede cognitive impairment, it may be _________?
Parkinson’s disease
When cognitive impairment precedes motor deficits, it may be _________?
Dementia with Lewy Bodies
The following symptoms are associated to which type of dementia? hallucinations visuospatial impairment sleep disturbance fluctuating attention and vigilance gain imbalances reduced speech rate and fluency executive function impairments
Dementia with Lewy Bodies
Frontotemporal Dementia accounts for 10% of dementia cases, most are diagnosed ______ the age of 65.
before
What is a nonspecific term that describes a disease or disorder of the brain?
Encephalopathy
What alters the brains functions and / or structure of the left and right hemispheres?
Encephalopathy
A higher percentage of geriatrics have what?
Encephalopathy
Approximately what percent of those with encephalopathy are in surgical ICU’s?
20-30%
What are presenting features of encephalopathy? Mark all that apply.
A. Acute change in mental state
B. Change in personality, behavior, and in cognitive functioning
C. Altered level of alertness
D. Inattentiveness, Lethargy, and Distractibility
E. All of the above
E. All of the above
Examples of encephalopathy etiologies include •Infection (bacterial, viral) •Dehydration, poor nutrition •Metabolic deficiency •Hypoglycemia •Diabetic ketoacidosis •Drug intoxication •Anoxia •Uremia •Meningitis •\_\_\_\_\_\_ \_\_\_\_\_\_\_\_
Brain Tumors
Right Hemisphere Brain Damage:
Characteristics include both: _____ and ______ deficits
Cognitive; Communication
Right Hemisphere Brain Damage: Cognitive deficits- (AEA) 1. 2. 3.
Attention
Executive function
Awareness of deficits (anosognosia)
Right Hemisphere Brain Damage: Communication deficits- (PCPP) 1. 2. 3. 4.
Prosody (aprosodia)
Comprehension
Production
Pragmatics
Right Hemisphere Brain Damage: Attention difficulty with- (SAUS) 1. 2. 3. 4.
Sustained
Alternating
Unilateral neglect
Selective
Right Hemisphere Brain Damage:
Unilateral neglect is ____ a visual deficit
NOT
Right Hemisphere Brain Damage:
Unilateral neglect can occur following damage to _____ henisphere.
Either
Right Hemisphere Brain Damage:
Types of neglect:
1.
2.
Left (due to RHD)
Right (due to LHD)
Right Hemisphere Brain Damage:
Types of neglect-
____ neglect is most common, more severe, and lasts longer. ____ neglect is less common, less severe, and resolves more quickly.
Left
Right
Right Hemisphere Brain Damage: Types of neglect- Can affect various modalities: (MAT) 1. 2. 3.
- Motor
- Auditory
- Tactile
Right Hemisphere Brain Damage:
Types of neglect-
______ (UVN) affects one’s ability to attend to visual information from the left visual field or left side of an object
Unilateral visuospatial
Right Hemisphere Brain Damage: Types of Unilateral Neglect- 1. 2. 3.
Viewer centered
Object centered
Combinaiton
Right Hemisphere Brain Damage: Region of space- \_\_\_\_\_\_ space: one's own body \_\_-\_\_\_\_ space: within reaching distance \_\_\_\_-\_\_\_\_ space: beyond arm's reach
Personal
Peri-personal
Extra-personal
Right Hemisphere Brain Damage:
Neglect & Language-
Can affect _____ & _____.
Reading; writing
Right Hemisphere Brain Damage:
Neglect dyslexia: omit, substitute letters on the ____ side of words/sentences
left
Right Hemisphere Brain Damage:
Neglect dysgraphia: begin ____ in the middle or on the right side of the page.
writing
Right Hemisphere Brain Damage:
Executive Function deficits caused by ___ are well-documented. data specific to RHD vs stroke is ____.
Stroke; limited