Quiz 3 Flashcards
Increased CO raises what and decreases what
Raises Pulm pressures
Decreases PVR
What 2 positions are hydrostatic pressure minimized?
Prone or supine
What conditions cause a zone 4 in the lung?
- high pulm pressures (eg LV failure or Mitral stenosis)
- Pulm edema
- increased resistance & low blood flow
Different pressures in what 3 things create lung zones?
- Arteries (a)
- Veins (V)
- Alveoli (A)
Most active regulation of pulmonary vessels is mediated by what
Local metabolic influences
What is a potent vasodilator and a platelet activation inhibitor?
Prostacyclin
Causes vasodilation through smooth muscle relaxation through synthesis of cyclic GMP
Nitric Oxide
What is a critical factor governing pulmonary circulation?
Partial pressure of O2 in alveoli
What is an important mechanism in regulation V/Q ratio?
Hypoxic Pulmonary Vasoconstriction (HPV)
What zone does positive pressure ventilation effect?
Zone 2
How do you decrease PVR?
- Recruitment (main way)
- Distention