Quiz 2: Neurons, Muscles, CNS, PNS, ANS, and BBB Flashcards
In what way are cardiac and skeletal muscles similar?
5
Both have troponin complexes.
Both have striations.
Both express L-type channels on the cell membrane.
Both require the action potential to trigger contraction.
Both are regulated by the autonomic nervous system.
Which of the following is a direct result of depolarization of presynaptic terminal?
Voltage-gated Ca2+ channels in the membrane open.
Oligodendrocytes and Schwann cells differ in what way?
Oligodendrocytes are found in the CNS, whereas Schwann cells are found in the PNS.
At a chemical synapse, an action potential arriving at the presynaptic terminal triggers the release of transmitters by (3)
Activating voltage-gated Ca2+ channels.
Depolarizing the presynaptic terminal.
Triggering exocytosis.
Which of the following statements is true regarding smooth muscles?
(1)
Unlike skeletal muscles, they do not have troponin complexes.
Which of the following statements is true regarding smooth muscles?
(2)
They are under the influence of both cholinergic and adrenergic nerve terminals.
Action potentials are not always required to initiate contraction.
The binding sites for the cross-bridges are located on (2)
Actin
Myosin head
What structure does calcium bind to when smooth muscle contraction is initiated?
Calmodulin
Which of the following statements are true?
A. The SR is the only source of Ca2+ ions.
B. There are different forms of myosin and virtually all eukaryotic cells contain myosin.
C. Troponins are regulatory proteins on the thin filament.
D. When myosin light chain kinase (MLCK) activity is greater than myosin light chain phosphatase (MLCP) activity, cross-bridge cycling can occur.
E. An increase in cytosol Ca2+ is always required for muscle contraction.
B. There are different forms of myosin and virtually all eukaryotic cells contain myosin.
C. Troponins are regulatory proteins on the thin filament.
D. When myosin light chain kinase (MLCK) activity is greater than myosin light chain phosphatase (MLCP) activity, cross-bridge cycling can occur.
Cross bridges form between?
actin and myosin
Which of the following statements are true?
A. Gap junctions are found on cardiac and smooth muscles, but not on skeletal muscles.
B. Ach always excites muscle cells and causes muscle contraction.
C. All nerve terminals innervating muscle cells release Ach
D. Muscle relaxation always occurs as Ca2+ is removed from the cytosol.
E. Binding of IP3 to ligand-gated Ca2+ channels causes Ca2+ release from the SR.
F. Gap junctions are found on cardiac muscles, but not skeletal and smooth muscles.
A. Gap junctions are found on cardiac and smooth muscles, but not on skeletal muscles.
E. Binding of IP3 to ligand-gated Ca2+ channels causes Ca2+ release from the SR.
The troponin/tropomyosin complex is associated directly with which of the following? (2)
Actin
The thin filament
When transmitters bind to their receptors, they may
A. Hyperpolarize postsynaptic neurons
B. Produce changes in 2nd messengers
C. Produce no effect on the membrane potential
D. Depolarize postsynaptic neurons
E. Alter gene expression
F. Decrease presynaptic transmitter release
G. Increase presynaptic transmitter release
All of the choices are correct.
What is a neuromuscular junction?
3
An excitatory synapse.
A cholinergic synapse.
A synapse between a motor neuron and a skeletal muscle cell
Which of the following may lead to an inhibition of synaptic transmission?
A. Blockade of the enzymes responsible for degradation of the transmitter
B. Uptake of the transmitters into postsynaptic neurons
C. Inhibition of the transport of the transmitter into synaptic vesicles
D. Reuptake of the transmitter into presynaptic terminals
E. Uptake of the transmitters into glia cells
F. Hyperpolarization of presynaptic neurons
G. Blockade of postsynaptic receptors
H. Blockade of Ca2+ channels on the presynaptic terminal
I. Blockade signaling pathways linked to postsynaptic receptors
J. Blockade of the interaction between v-SNAREs and t-SNAREs
K. Inhibition of the synthesis of the transmitter
L. Hyperpolarization of postsynaptic neurons
M. Blockade of Na+ channels on the presynaptic terminal
N. Blockade of K+ channels on the presynaptic terminal
A. NOT CORRECT
B. NOT CORRECT
C. Inhibition of the transport of the transmitter into synaptic vesicles
D. Reuptake of the transmitter into presynaptic terminals
E. Uptake of the transmitters into glia cells
F. Hyperpolarization of presynaptic neurons
G. Blockade of postsynaptic receptors
H. Blockade of Ca2+ channels on the presynaptic terminal
I. Blockade signaling pathways linked to postsynaptic receptors
J. Blockade of the interaction between v-SNAREs and t-SNAREs
K. Inhibition of the synthesis of the transmitter
L. NOT CORRECT
M. Blockade of Na+ channels on the presynaptic terminal
N. NOT CORRECT
After a transmitter is released into the synaptic cleft, which of the following may terminate the action of the transmitter?
(3)
Uptake of the transmitter into the presynaptic terminal
Enzymatic degradation of the transmitter
Diffusion of the transmitter away from the synapse