quiz 2 (nerve impluse) Flashcards
what is nerve impluse
Consists of a series of action
potentials
where does action potenital occur in Unmyelinated Neurons
Action potential occurs all along the axon
where does action potential occur in Myelinated Neurons
Action potential jumps from between the nodes
which type of neuron would the action potential occur faster in
myelinated
How Does Nerve Impulse
Move?
-Areas of axon where
action potential just
occurred are in
refractory period so
cannot be stimulated
yet
-Prevents impulses
from traveling
backwards
Ligand-gated Channels-
AP
also referred as ionotropic receptors, are a group of transmembrane ion-channel proteins which open to allow ions such as Na+, K+, Ca2+, and/or Cl− to pass through the membrane in response to the binding of a
chemical messenger (i.e. a ligand), such as a neurotransmitter.
The Synapse
Small space
between neurons or
between a neuron
and an effector
The space between
a neuron and a
muscle is called
neuromuscular
junction
Neurotransmitter
Chemical messenger
released across the
synapse
Can be excitatory or
inhibitory
Excitatory Neurotransmitter
Excitatory: receptor
proteins trigger
sodium channels to
open causing
depolarization lowering
threshold level
inhibitory Neurotransmitter
inhibitory: receptor
proteins trigger
potassium channels
to open causing
hyperpolarization
Acetylcholine
Neurotransmitter across
neuromuscular junction
Excites muscle cells
causing depolarization
and contraction
If remained in synaptic
cleft, muscle would
remain excited
(dangerous for heart and
diaphragm)
Excitatory to skeletal
muscles; excitatory or
inhibitory at other
locations
Cholinesterase
An enzyme that
destroys
acetylcholine
This closes Na+
channels allowing a
recovery phase
Nerve gas and some
insecticides work to
block release of
cholinesterase
Summation
When one postsynaptic
neuron is excited by
more than one
presynaptic neuron.
* More realistic
representation of
neurons in body
Effects of stimulants on neurotransmission
Drug mimics neurotransmitter, stimulating receptor
* Drug decreases rate of breakdown or diffusion of
neurotransmitter from receptor site
* Drug increases rate of release from presynaptic neuron