Quiz 2 Flashcards
How long would you wait to see results of a allergy skin test?
20 - 30 min
What mutation exists in Dubin-Johnson Syndrome?
Multidrug Resistance Associated Protein 2 (MRP2)
What modulates Na absorption and K secretion in the colon?
Aldosterone
What protein binds copper to enter circulation?
Ceruloplasmin
What does long-chain free fatty acid Palmitate bind on adipocytes, causing inflammation?
TLR-4
Both Zollinger-Ellison Syndrome and Duodenal Ulcers are caused by beefed up parietal cells juiced up on gastrin. What distinguishes the two disorders?
Zollinger-Ellison: Caused by Pancreatic Tumor
Duodenal Ulcer: Caused by food ingestion response
Somatostatin decreases gastric H+ by stimulating Gi and inhibiting two kinds of cells. What are they?
ECL cells (histamine) G cells` (gastrin)
What does the male membranous urethra pass through?
Urogenital Diaphragm
What does NABQ1 do?
Free-Radical Peroxidizing / Damage to the Liver
How does Cholera increase Cl- Secretion?
increased cAMP secretion
What does cholesterol ester hydrolase do?
Catalyzes production of free cholesterol
Hydrolyzes TAGS into glycerol
Where is glucagon stored?
Dense Granules of a-cells
What are bile acids and bile salts synthesized from?
Hepatic Choleterol
What is the difference between a bile salt and a bile acid?
A bile acid is protonated
What is the downstream pathway of the H2 receptor?
Uses Gs to simulate cAMP to make H+
What is the significance of the North-South gradient of DMI?
It may be linked to Vitamin D deficiency (and wheat gluten, just didnt want to make another card)
Why can C Peptide be a marker for Endogenous Insulin Secretion?
Its cleaved and packaged alongside Pro-Insulin, and those two are equally released together in the blood
What supplies blood to the vascular smooth muscle of the dick?
Helicine As
Where is sperm mainly stored?
Epididymis
What two cytokines do Th1 cells release in DMI, and what do they do (leading to b-cell destruction)?
IFN-y: Activates Macrophages
IL-2: Activation of Auto-Ag specific CD8 T Cells
What are the lateral boundaries of the perineum?
Ischiopubic Rami
Sacrotuberous Ligaments
What effect does interruption of enterohepatic circulation have on bile?
Increases synthesis (up to 10x)
What do Prostaglandins act on to decrease H+ secretion in the stomach?
Inhibit ECL cells (histamine)
Stimulate Gi
What two effects do mutations in the CFTR gene have that cause Cystic Fibrosis?
Disrupts Cl- channel on the apical pancreatic duct cells
Loss of HCO3- secretion (may lead to pancreatitis)