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pharmacology/ toxicology > Quiz 2 > Flashcards

Quiz 2 Flashcards

1
Q
  1. What does botulism do at the neuromuscular junction?
A

a. Blocks acetylcholinesterase

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2
Q
  1. Neostigmine…
A

a. Inhibits cholineesterase

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3
Q
  1. Cholinergic agonist…
A

a. increases GI motility

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4
Q
  1. Adverse effect of cholinergic agonist..
A

a. diarrhea

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5
Q
  1. tubocurarine is a …
A

a. neuromuscular blocker

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6
Q
  1. nicotine…
A

a. nicotinic ganglion blocker

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7
Q
  1. Neostigmine used to treat..
A

a. myasthenia gravis

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8
Q
  1. Adverse effect of atropine..
A

a. Mydriasis

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9
Q
  1. mechanism of cholinergic agonist
A

?

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10
Q
  1. adverse effect of succinylcholine…
A

a. increase body temperature

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11
Q

Acetylcholine actions include…

A

Decrease HR & BP, increase GI motility & secretions, cause miosis

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12
Q

What cholinergic receptors are excitatory on the heart, smooth ms, brain & exocrine glands?

A

Muscarinic M1

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13
Q

What cholinergic receptors are inhibitory on the adrenal medulla, ganglia, and neuromuscular junctions?

A

Muscarinic M2

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14
Q

What are the adverse effects of cholinergic drugs?

A

Diarrhea, diaphoresis, miosis, nausea, urinary urgency

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15
Q

What is used in atropine overdose?

A

Physostigmine

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16
Q

What is used for Myasthenia gravis, and as an antidote for tubocurarine?

A

Neostigmine

17
Q

Neostigmine can be reactivated by…

A

PAM/pralidoxime

18
Q

In small doses, what are the actions of nicotine?

A

Stimulant: Increase HR, BP, peristalsis and secretions

19
Q

In high doses, what are the actions of nicotine?

A

Blocker: Decreased HR, peristalsis and secretions-block ANS@nicotinic receptors

20
Q

What is used during the induction of anesthesia, & during electroconvulsive shock treatment?

A

Succinylcholine

21
Q

What are the side effects of Succinylcholine?

A

Malignant hypertension & post-operative muscle pain

22
Q

What is used during surgery to relax skeletal muscle?

A

Tubocurarine

pharmacology/ toxicology (7 decks)

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