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CPD Fall 2014 > Quiz 10 > Flashcards

Quiz 10 Flashcards

1
Q

Howell Jolly bodies and hypersegmented PMNs

A

Macrocytic anemia

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2
Q

Low Iron, low ferritin, high TIBC

A

Iron deficiency anemia

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3
Q

Sx of iron deficiency anemia

A

Sx: HA, irritability, loss of stamina, increased pallor, difficult concentration
Severe deficiencies – pica, glossitis, cheilosis, concave nails, increased heart rate, dyspnea, restless leg syndrome, glossal pain, reduced salivary flow leading to dry mouth,

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4
Q

Labs for Iron Deficiency Anemia

A

CBC/smear
Stool blood
Iron Absorption
Iron, TIBC, ferritin

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5
Q

Labs for Sideroblastic Anemia

A

CBC/smear
Iron Ferritin
BM biopsy
Lead screen

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6
Q

Labs for Anemia of Chronic Dz

A

CBC/smear
Iron, Ferritin, Transferrin
ESR, CRP
EPO Epogen

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7
Q

Target cells, stippling, polychromatophilic, erythroid hyperplasia in BM.
High iron, ferritin, transferrin

A

Sideroblastic anemia

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8
Q

Microcytic, hypochromic

Bone marrow responsiveness to erythropoietin is mediated by inflammatory cytokines

A

Anemia of chronic dz

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9
Q

Causes of anemia of chronic dz

A

• Causes: infectious, inflammatory, neoplastic disease, severe trauma, heart failure, diabetes mellitus, anemia of the elderly, and acute or chronic immune activation

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10
Q

Labs for Hypoproliferative Anemia

A

CBC/smear
Creatinine clearance
TSH
BM biopsy

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11
Q

Low marrow activity due to lack of EPO or inability of marrow to respond to it

A

Hypoproliferative Anemia

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12
Q

Pancytopenia of all cell lines

A

Aplastic/Hypoplastic anemia

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13
Q

Thrombocytopenia: ecchymosis, petechiae, bleeding from gums, ocular fundi

A

Aplastic/Hypoplastic anemia

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14
Q

Causes: Chemical exposure: drugs, pesticides, industrial chemicals, benzenes, anti-cancer agents (unknown mechanisms). Infections such as Parvo-B19, HIV

A

Aplastic/Hypoplastic anemia

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15
Q

Labs for Aplastic Anemia

A

CBC/smear
Iron
RET
BM aspiration (Acellular bone marrow)

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16
Q

Marrow is replaced by a tumor, granuloma, lipid storage diseases, or fibrosis

A

Myelophthisic anemia

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17
Q

Labs for Myelophthisic anemia

A

CBC/smear

BM biopsy

18
Q

Anisocytosis, poikilocytosis, nucleated RBCs, immature myeloid cells

A

Myelophthisic anemia

19
Q

Neurological signs, glossitis, diarrhea, muscle wasting

A

Macrocytic anemia

20
Q

MCV > 95-100, aniso, poikilo, high RDW

A

Macrocytic anemia

21
Q

Labs for Macrocytic anemia

A

CBC/smear

B12/folate

22
Q

Autoimmune Hemolytic anemia: warm is assocated with RBC breakdown in ______ cold is associated with breakdown in ______

A

Warm - spleen

Cold - liver

23
Q

Labs for Autoimmune Hemolytic anemia

A

Coombs test

24
Q

MCV low/norm, MCHC high, aniso, high LDH and bilirubin, low haptoglobin

A

Hereditary Spherocytosis, Elliptocytosis

25
Q

High RET, Heinz bodies and bite cells

A

G6PD anemia

26
Q

Labs for G6PD anemia

A

G6PD assay

27
Q

Norm MCV, Norm/High WBC, nucleated RBC, high plasma Hgb, high haptoglobin

A

Sickle Cell anemia

28
Q

SX of Sickle Cell anemia

A

Abd pain/vomit, bone pain, leg ulcers, myalgia, hematuria

29
Q

Labs for Sickle Cell anemia

A

Hgb electrophoresis

30
Q

Norm MCH, 30-100% target cells and spherocytes

A

Hgb C Disease

31
Q

Low MCV, low MCH, marked aniso and poiklilocytosis, target cells, stippling, nucleated RBC, norm/high iron

A

Thalassemia

32
Q

Labs for Thalassemia

A

Hgb electrophoresis

33
Q

leg ulcers, gallstones

A

Thalassemia

34
Q

Labs for Neutropenia

A

CBC, bact & fung blood cultures, skin lesion biopsy, UA, CXR, Radiography of sinuses, BM biopsy

35
Q

Low PMNs, granulocytes

A

Neutropenia

36
Q

Low lymphocytes

A

Lymphocytopenia

37
Q

Diminished tonsils/lymph nodes, LAD

A

Lymphocytopenia

38
Q

List the categories of severity of Neutropenia and give the severity

A

1000-1500/mm3 mild risk infx
500-1000/mm3 mod risk infx
<200/mm3 – rapidly fatal infx

39
Q

Sx of severe Neutropenia

A

Cellulitis, liver abscesses, furunculosis, pneumonia, and septicemia

40
Q

What levels of lymphocytes define Lymphocytopenia?

A

< 3000/mm3 in children <2 yo

CPD Fall 2014 (12 decks)

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