Quiz 1 Flashcards
What are some characteristics of oxytocin?
Short half life, inhibited by progesterone, works w/ estrogen
Both ADH and Oxytocin are sythezied by _____________ cells.
neurosecretory
What are some general characteristics of prolactin
speciea variability and its a protein hormone
What are some general characteristics of GH?
Short half-life, species variablity
What are the functions of GH?
Protein synthesis, glucose release, increase insulin resistance, lipolysis
What are internal factors stimulating GH secretion?
Decreased serum glucose and amino acids
What is the disease created by insufficient GH hormone release?
panhypopituitarism
_________ is the disease associated with excess E and NE
Pheochromocytoma
What are signs/symptoms of pheochromocytoma?
hypertension, panting, tachycardia, muscle atrophy
What are two major types of proteins that bind to thyroxine?
Albumin and Thyroid Binding Globulin (TBG)
What is the most common form of hypothyroidism?
Primary
What are some signs of hypothyroidism?
weight gain, fatigue, alopecia
What are two causes of hypothyroidism?
idiopathic atrophy and Lymphocytic thyroidistis (autoimmune)
What is unusual about the signalment of hypothyroidism?
It usually is diagnosed is middle aged dogs
What are signs/symptoms of hyperthyroidism?
Weight loss, goiter, tachycardia, intolerance to heat, bulging eyeball
What are 2 causes of hyperthyroidism?
multinodular adenomatous goiter and carcinoma
Methimazole inhibits __________
thyroidal peroxidase enzyme (TPO)
_______ is a precursor form of MMI currently used in Europe
Carbimazole
_______ is an antithyroid drug that is more effective than MMI but also causes a rare autoimmune disease
Propylthiouracil (PTU)
Why is radioactive Iodine the treatment of choice for hyperthyroidism?
safest, least stressful, most specific, curative, spares parathyroid
______ divides glands into lobes
Trabeculae
Pinealocytes of the pineal gland produce ________
melatonin
Both Oxytocin and ADH belong to what class of hormones?
Peptide Hormones
T/F- Oxytocin and ADH are highly conserved from species to species
T