Quinolonas Flashcards

0
Q

De qué espectro son las quinolonas ?

A

Amplio

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1
Q

Las quinolonas son bactericidas o bacteriostaticas?

A

Bactericidas

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2
Q

Mecanismo de acción de las quinolonas

A

Inhibición de la enzima DNA girasa y topoisomerasa II

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3
Q

Las quinolonas actúan sobre los microorganismos

A

Gram negativos

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4
Q

Como se clasifican?

A
Fluoradas y no fluoradas
Por generaciones (4)
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5
Q

Primera generación no fluoradas

A

Ácido nalidixico
Cinoxacina
Acido pipemidico
Ácido oxolinico

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6
Q

Primera generación fluoradas

A

Frente a enterobacterias causales de infecciones urinarias

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7
Q

Segunda generación no fluoradas

A

Activos frente aerobios gram negativos

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8
Q

Segunda generación fluoradas

A
Ofloxacina!
Norfloxacina
Ciprofloxacina
Nodifloxacina
Levofloxacina
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9
Q

Tercera generación no fluoradas

A

Frente aerobios gram negativos y cocos gram positivos

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10
Q

Tercera generación fluoradas

A

Lomefloxacina
Esparfloxacin
Tosufloxacina
Clinsfloxacina

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11
Q

Cuarta generación no fluoradas

A

Activos frente aerobios gram negativos y cocos grM positivos abaerobios

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12
Q

Cuarta generación fluoradas

A

Gatifloxacina

Moxifloxacina

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13
Q

Indicaciones de las quinolonas

A

Infecciones vías urinarias
Prostatitis
Infecciones de transmisión sexual, vías resporatorias, tuvo digestivo y abdomen, huesos articulaciones y tejidos blandos

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14
Q

ContrIndicacions

A

Efectos negativos en tuvo digestivo ( tomar con alimentos )

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