Quinolines and Quinolones Flashcards

1
Q

Skraup synthesis

A

amine and glycerol with H2SO4, PhNO2 ([O] to regain aromaticity)

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2
Q

Doebner-von-miller synthesis

A

amine and a,b-unsat ketone with LA catalyst for conj addition and FeCl3 ([O])

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3
Q

Combes synthesis

A

amine and 1,3-diketone uses imine formation

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4
Q
A
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