questions Moldx

Question 1

Retinoblastoma gene mutations:

Answer 1

Can be hereditary or non-hereditary caused by mutations in the RB1 tumor suppressor gene. Autosomal dominant inheritance or one mutation and another mutation is acquired in the retinal cells in early childhood. Greatly increases the risk of developing cancer of the eye.

Question 2

Mutations in these genes are associated with hereditary colon cancer

Answer 2

Lynch Syndrome is caused by mutations in MLH1, MSH2, MSH6, PMS2, and EPCAM.

Question 3

Mutations associated with lung cancer

Answer 3

EGFR and KRAS mutations render them constitutively active, signaling cell proliferation

Question 4

EGFR

Question 5

MLH1, MSH2, MSH6 are

Question 6

large and small subunits of Ribosome

Question 7

rRNA

Question 8

Nonsense and exon skipping

Question 9

RAS mutations

Question 10

exonuclease and endonuclease

Question 11

telocentric

Question 12

MSI

Question 13

fragile X

Question 14

Huntington disease

Question 15

C an N terminus

Question 16

tata box

Question 17

how to identify ras mutations

Question 18

muscular distropy

Question 19

CFTR

Question 20

Angelman vs Prader-willi

Question 21

hplc

Question 22

allelic discrimination primes gc clamp

Question 23

retrotranposon

Question 24

HIV significant log change

Question 25

HCV testing

Question 26

Gating in flow cytomerty

Question 27

Sensitivity, specificity PPV, NPV

Question 28

Calculate number of amplicons present after 40 cycles 1000 target

Question 29

ribosomal RNA

Question 30

15-17 tranlocation

Question 31

Add what to GC rich regions to sequence

Question 32

Centormere is rich in which bases

Question 33

NGS and the number of reference bps?

Question 34

TMA

Question 35

HCA

Question 36

PGXm sensitive drugs

Question 37

heterogeneity

Question 38

fold difference delta CT

Question 39

how many employees to accommodate a disabled person

Question 40

pregnant woman is exposed to a chemical at work, what to do?

Question 41

Someone died how long to notify osha

Question 42

what chemicals do each class of the fire extinguishers contain

Question 43

Z score

Question 44

SD

Question 45

Who gets employee medical records if lab goes bancrupt

Question 46

sealed-bid pricing

Question 47

Medicare parts

Question 48

ICD-10 procedural codes

Question 49

Latent error

Question 50

most errors happen in what phase of testing?

Question 51

Licensure

Question 52

RCF and rpm weight, radius…

Question 53

serial dilution

Question 54

hazarous material applies to what substances

Question 55

packaging and shipping

Question 56

referral testing

Question 57

Who must train an employee in bloodborne pathogens? How long after hired