Questions

Question 0

Describe the integration between osteoblasts and osteoclasts in bone formation.

Answer 0

Size of a bone increases as osteoblasts build new bone on the outer surface of the bone while osteoclasts increase the size on the medullary cavity by breaking down existing bone.
NOTE: once a bone has reached its mature size this process of osteogenesis and reabsorption continues to take place but is in balance with each other in the healthy individual.

Question 1

How does bone growth occur?

Answer 1

Bone ossification occurs from the synthesis of bones organic matrix by osteoblasts, followed immediately by the calcification of this matrix.

This ossification begins in the diaphysis and in the epiphysis progressing towards the epiphyseal plates which are the last to ossify when a person reaches skeletal maturity.

Question 2

Explain Wolff’s Law.

Answer 2

Wolff’s law states that every change in form and function of a bone or it’s function alone is followed by certain definite changes in its internal architecture.

Question 3

How fast do nerves regenerate?

Answer 3

Regeneration of nerves is slow, about 3-4mm per day and can only regenerate is the mylin sheath is intact.
NOTE: regeneration is poor and slow in the CNS as compared to nerves in the peripheral nervous system.

Question 4

Name the phases of inflammation

Answer 4

1. Inflammation response phase 1-4 days
2. Repair and regeneration phase 4days-6wk
3. Maturation- remodeling phase 6wk-3 years

time table taken from arnhiem