Questions Flashcards
true vocal cords
stratified squamous
paranasal sinus, laryngeal vestibule, false vocal cords, trachea
ciliated pseudostratified columnar mucus
pseudomonas
ecthyma gangrenosum; exotoxins perivascular
acute manic
lithium, valporate, carbamazepine + atypical (olanzipine)
wiskott-aldrich
thrombocytopenia, eczema, purpura; IgM low
immediate hypersensitivity
mast cells and basophils
Eosinophils
defense against parasites: when a parasite enters the bloodstream, binds to free IgE; this binds to an IgE Fc receptor (heavy chain) located on the eosinophil cell surface. Eosinophil –> major basic protein and other enzymes from its granules, substances that damage and destroy the antibody parasites. Antibody-dependent cellular killing (macrophages and NK cells also do this)
how to eosinophils regular type 1 hypersensitivity reactions
histaminase –> helps with atopic symptoms, granules also contain leukotrienes and peroxidases that facilitate inflammation
penetrating injury to the neck superior to cricoid cartilage injuries what nerve
ansa cervicalis
what is responsible for intimal thickening after intimal injury
smooth muscle cells –> synthesis of new collage, elastin, and proteoglycans
when does PPV increase
increase disease prevalence
when does NPV increase
decrease disease prevalence
what does carbidopa do in terms of side effects
lowers the peripheral side effects: nausea, vomiting, ventral extrasystoles, a. fib, postural hypotension; behavioral changes from levdopa worsen
tetrodotoxin
potent neurotoxin found in pufferfish; blocks voltage gated sodium channels in nerve membranes (passive transport)
NNRTIs
don’t rquire activation via intracellular phosphorylation: nevirapine, efavirenz, delavirdine
what happens when ribosome encounters a stop codon
releasing factors bind to the ribosome and stimulate release of the formed polypeptide chain and dissolution of the ribosome mRNA complex
neonatal opioid withdrawal
pupillary dilation, rhinorrhea, sneezing, nasal stuffiness, diarrhea, NV, shrill crying, tremor, seizures; tx: opium solution
astrocytes
tissue repair –> irreversible neuronal damage = gliosis –> scar –> glial hyperplasia Qstem: neuronal shrinkage and intense cytoplasmic eosinophilia
ARDS
Qstem: AA –> UTI–> shock, what is the lung look like: fluid accumulation in the alveolar spaces and alveolar hyaline membrane formation
zolpidem
short acting hypnotic agent, structurally unrelated to to benzos but binds to the same protion of GABAa receptor and increases the inhibitor actions of GABA on the CNS; treats insomnia, rapid onset, less potential for dependence
colonizing aspergillosis
old lung –> TB, emphysema, sarcoid; doesn’t invade lung tissue but grows inside the cavity –> fungus ball, asymptomatic may cough and hemoptysis
hypersensitivity aspergillosis
asthma, ABPA, wheezing fever migratory pulm infitrates
invasive aspergillosis
immunosuppressed, cough hemoptysis, pleuritic chest pain and fever, necrotizing pneumonia and granuloma formation, invades tissue, extrapulmonary involvement
propionyl CoA carboxylase defieicny
inccrease prop CoA –> poor feeding, vomiting, hypotonia, lethargy, anion gap acidosis