questions Flashcards
where would a phaeochromocytoma be found
adrenal medulla
phaeochromocytoma associated with
MEN type II
neurofibromatosis
von hippel-lindau
what is orlistat
anti-obesity drugs
what signalling pathway does GH use
the tyrosine kinase receptor pathway > activation of Janus Kinase > signalling transduction and activation of transcription (STAT)
de quervains thyroiditis
occurs in women post viral infection
presents with thyrotoxicosis which can change to hypothyroidism
histological findings of papillary carcinoma of the thyroid
change in nucleus shape and size and nuclear membrane irregularity
presentation of carcinoid syndrome
diarrhoea facial flushing wheeze abdominal pain tachycardia hypotension
what improves symptoms in carcinoid syndrome
somatostatin analogues- octreotide
what is congenital adrenal hyperplasia
congenital deficiency of 21-hydroxyalse enzyme which causes underproduction of cortisol and aldosterone and over production of androgens
inheritance of congenital adrenal hyperplasia
autosomal recessive
main glucocorticoid hormone
cortisol
main mineralocorticoid
aldosterone
function of mineralocorticoids
act on the kidneys to control the balance of salt and water in the blood
what is testosterone
an androgen
what does 21-hydroxylase do
convert progesterone into aldosterone and cortisol
