Question Rewiew Flashcards

1
Q

most common noscomial blood stream infection

A

Coag neg Staph, Staph Aureus, Enterococci, Candida

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2
Q

Primary signs of bacterial vaginosis

A

Fishy odor, no vaginal inflammation, elevated pH greater than 4.5, positive with test. Likely pathogen, G, vagnilis. Treat with metronidazole clue cells

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3
Q

Signs of Trichomonas

A

yellow-green, frothy discharge. PH above 4.5, trichomonads on smear, treat with metronidazole and also treat sexual partner. Presence of vaginal inflammation

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4
Q

Primary signs of Candida vaginitis

A

Cottage cheese appearance, presence of vaginal information, lower pH, pseudohyphae, treat with fluconazole

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5
Q

Decreased amount of glycogen from the vaginal epithelium can be a sign of

A

Atrophic vaginitis secondary to menopause

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6
Q

Causes of Candida vaginitis

A

antibiotics, contraceptive use (especially with high estrogen), corticosteroid therapy, diabetes, immunosuppression.

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7
Q

Haemophilus influenza - signs, upper respiratory , x-ray,

A

Acute fever, inspiratory strider, drooling, odynophagia, positive thumb sign on lateral cervical x-ray due to edematous epiglottis,

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8
Q

Haemophilus influenza – composition of the capsule.

A

Polyroibosyl-ribitol-phosphate, antibodies to the capsule specifically to PRP lead to opsonization. First vaccine is given at two months old

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9
Q

Brucella - transmission, signs

A

acquired by drinking infected milk or by direct contact with infected sheep or goats fever, malaise, lymphadenopathy, hepatosplenomegaly

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10
Q

Campylobacter fetus prefers to infect…

A

Immunocompromised individuals and newborns, pregnant women in their third trimester, and debilitated elderly people, leading to septicemia

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11
Q

Function of protein a in stph aureus

A

bind Fc portions of IgG molecules thereby preventing phagocytosis and complement fixation.

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12
Q

Bacteria that makes intracellular polyphosphate granules

A

Corynebacterium diphtheriae - visualized using methylene blue

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13
Q

Colonizing aspergillosis - nature of infection

A

colonizes old lung cavities (TB, emphysema, sarcoidosis), does not grow into tissue, makes fungus ball or aspergilloma, may be asymptomatic or lead to cough or hemoptysis.

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14
Q

Hypersensitivity reactions to Aspergillus lead to…

A

Allergic bronchopulmonary aspergillosis causing wheezing fever migratory pulmonary infiltrates

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15
Q

Invasive aspergillosis occurs primarily in the…

A

Immunocompromised and neutropenic patients with primary lung involvement leading to cough hemoptysis, pleuritic chest pain and fever. Eventually that necrotizing pneumonia and granuloma formation occur,extrapulmonary involvement, like within the brain is not unusual.

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16
Q

Bartonella can cause what infection syndrome? , And what patients, signs?

A

Bacillary angiomatosis, mostly an immune compromised patients, red Papular rash, that can be found on the skin or the viscera. Can be fatal if left untreated

17
Q

Streptococcus and protein M - function

A

inhibits phagocytosis and activation of complement, the major virulence factor for group a strep. Cytotoxic for neutrophils, mitigates bacterial attachment. Antigenic

18
Q

Streptolysin O - properties

A

oxygen labile immunogenic extracellular protein made by Streptococcus pyogenes. Lyses red blood cells (making the bacteria beta hemolytic) and neutrophils. Anybody responsible for positive test for ASO titer. Does not increase resistance to phagocytosis

19
Q

Purpose of streptokinase

A

increased bacterial spread in infected tissue by catalyzing plasminogen to plasma, decreasing the thrombotic state in blood.

20
Q

Teichoic Acid

A

integrated into the peptidoglycan cell wall for some gram-positive bacteria. Have a minor LPS effect

21
Q

In order for virus to undergo reassortment in needs what kind of genome?

A

Segmented genome

22
Q

Primary Symptoms of Diptheria Infection, (mouth, constituional, neck.

A