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Class 22010 Lab > QBC STAR CBC INSTRUMENT > Flashcards

QBC STAR CBC INSTRUMENT Flashcards

1
Q

What are these results of?

  1. Hematocrit (Hct)
  2. Hemoglobin (Hgb)
  3. Mean Corpuscular Hemoglobin Concentration (MCHC)
  4. White Blood Cells (WBC)
  5. Granulocytes
  6. % Granulocytes
  7. Lymph/Mono
  8. % Lymph/Mono
  9. Platelets
A

Complete Blood Count (CBC) results

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2
Q

What is the most frequently ordered lab?

A

Complete Blood Count (CBC)

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3
Q

What supplies useful information regarding the concentration of the different cellular and non-cellular elements of blood and applies to multiple disorders?

A

CBC

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4
Q

What are some of the things that a CBC normally includes?

A
  1. Leukocyte (WBC) count
  2. Erythrocyte (RBC) count
  3. Hemoglobin (Hgb)
  4. Hematocrit (Hct)
  5. RBC indices
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5
Q

What is included with RBC indices?

A
  1. Mean Corpuscular Volume (MCV)
  2. Mean Corpuscular Hgb (MCH)
  3. Mean Corpuscular Hgb Concentration (MCHC)
  4. RBC distribution Width (RDW)
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6
Q

Is a platelet count normally included in a CBC?

A

Yes

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7
Q

What are the normal adult ranges for an RBC in a CBC?

A
  1. Males 4.5-5.9 x 106 cells/uL

2. Female 4.5-5.1 x 106 cells/uL

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8
Q

What is the number of red cells in a given volume of blood?

A

RBC

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9
Q

What are the normal adult ranges for Hemoglobin (Hgb) ?

A
  1. Males 14-17.5 g/dL

2. Females 12.3-15.3 g/dL

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10
Q

What is the main component of a red blood cell?

A

Hemoglobin

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11
Q

What is a protein that serves as a vehicle for the transportation of oxygen and carbon dioxide?

A

Hemoglobin

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12
Q

What provides a direct indication of the oxygen transportation capacity of the blood?

A

Hemoglobin (Hgb) concentration

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13
Q

What are the normal adult ranges for Hematocrit (Hct) ?

A
  1. Males 42-52%

2. Females 37-47%

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14
Q

What is the ratio of the volume of erythrocytes to that of the whole blood?

A

Hematocrit (Hct)

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15
Q

True or False

The Hematocrit (Hct) is usually 10 times the Hemoglobin (Hgb)

A

False

The Hematocrit (Hct) is usually 3 times the Hemoglobin (Hgb)

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16
Q

What are lab tests that are specifically used to assess red blood cell characteristics?

A

RBC indices

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17
Q

What is the normal range for the Mean Corpuscular Volume (MCV)

A

76-96 fL/cell

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18
Q

What is an estimate of the average volume (size) of RBC’s and is the most clinically useful of the RBC indices?

A

Mean corpuscular volume (MCV)

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19
Q

An increase in the MCV is normally associated with what?

A

Vitamin B12 or Folate deficiency

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20
Q

A decrease in the MCV is normally caused by what?

A

iron deficiency

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21
Q

What is the normal range for Mean Corpuscular Hemoglobin (MCH) ?

A

27-32pg/cell

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22
Q

What is known as the amount of hemoglobin per RBC?

A

Mean corpuscular Hemoglobin (MCH)

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23
Q

What is the normal range for the Mean Corpuscular Hemoglobin Concentration (MCHC)?

A

30-35 g/dL

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24
Q

What is known as the hemoglobin divided by the hematocrit?

A

Mean Corpuscular Hemoglobin Concentration (MCHC)

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25
Q

What is the normal range for the Platelet Count ?

A

150,000-400,000/uL

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26
Q

A low platelet count (<20,000 mm3) could make you at risk for what?

A

Hemorrhage

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27
Q

A high platelet count (>1,000,000/mm3) could put you at risk for what?

A

Thrombosis

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28
Q

What is abnormally high platelet count and has many causes such as stress or infection but may also be caused by: Splenectomy, Trauma, Iron deficiency anemia or Cirrhosis?

A

Thrombocytosis

29
Q

What is an abnormally low platelet count below 150,000/ mm3 this may be caused by various diseases such as TTP or DIC and may also be seen in leukemia and metastatic cancers?

A

Thrombocytopenia

30
Q

What is the normal WBC range?

A

4.5-11.0 x 103 cells/mm3

31
Q

What is considered a low WBC and what is considered a high WBC?

A

Low: <2,000/mm3
High: 30,000/mm3

32
Q

What is a low number of white blood cells referred to as?

A

Leukopenia

33
Q

These can all be causes for what?

  1. Bone marrow deficiency
  2. Collagen-vascular diseases
  3. Diseases of the liver or spleen
  4. Radiation therapy or exposure
A

Leukopenia

34
Q

What is a referred to as a high number of WBC’s?

A

Leukocytosis

35
Q

What could be some causes for leukocytosis?

A
  1. anemia
  2. bone marrow tumors
  3. infectious diseases
  4. Inflammatory disease
  5. leukemia
  6. emotional or physical stress
  7. Burns
36
Q

What is the normal range for neutrophils?

A

50-70%

37
Q

What is the normal range for bands?

A

0-5%

38
Q

What is the normal range for Eosinophils?

A

0-5%

39
Q

What is the normal range for basophils?

A

0-1%

40
Q

What is the normal range for monocytes?

A

1-6%

41
Q

What is the normal range of lymphocytes?

A

20-40%

42
Q

During an acute infection there is an increase in the percentage of what cells, resulting in what?

A
  1. Neutrophils

2. Neutrophilia

43
Q

Lymphocytosis (an increase in the total number of lymphocytes in relation to the total number of WBC) is typically an indication of what?

A

viral infection

44
Q

An increase in eosinophils (eosinophilia) is typical in what?

A

parasitic infections and allergic disorders

45
Q

How can you get the total for Mean Corpuscular Hemoglobin (MCH)?

A

MCH=Hgb x10 divided by RBC

46
Q

How can you get the total value of the Mean Corpuscular Hemoglobin Concentration (MCHC) ?

A

MCHC=Hgb/Hct x 100

47
Q

What is the ratio of the volume of erythrocytes to that of the whole blood?

A

Hematocrit

48
Q

What can be measured indirectly as the product of the MCV times RBC count in automated instruments?

A

Hematocrit

49
Q

What are the normal values for hematocrit in males and females ?

A

Males: 42-52%
Females: 37-47%

50
Q

What is the main function of hemoglobin?

A

to transport oxygen from the lungs

51
Q

What is the average concentration of hemoglobin in a given volume of packed red cells?

A

Mean Corpuscular Hemoglobin Concentration (MCHC)

MCHC = Hbg/Hct x 100

52
Q

What is the normal platelet count in adults?

A

150,000-400,000 platelets per microliter of blood

53
Q

What is the test used to determine the presence of an infection or leukemia ?

A

White blood cell count (WBC)

54
Q

How many types of granulocytes are there?

A

three

55
Q

What is a category of white blood cells characterized by the presence of granules in their cytoplasm?

A

Granulocytes

56
Q

What are the three types of granulocytes?

A
  1. Neutrophil Granulocytes
  2. Eosinophil Granulocytes
  3. Basophil Granulocytes
57
Q

What is the most abundant type of phagocyte and is important in defense against infectious disease?

A

Neutrophil granulocytes

50-70% of the total circulating white blood cells

58
Q

What granulocytes act as phagocytes and modulate inflammatory responses?

A

Eosinophil Granulocytes

59
Q

Normal adult peripheral blood contains what percentage of eosinophils?

A

0-5%

60
Q

What is one of the least abundant cells in blood with a percentage of 0-1%?

A

Basophil Granulocytes

61
Q

What are the second most numerous cell in the blood, comprising from 20-40% of the adult blood cells ?

A

Lymphocytes

62
Q

In adults, a finding of more than 4.0 x 10^9/L lymphocytes is defined as what ?

A

Lymphocytosis

63
Q

What is used to describe malignant appearing cells?

A

Atypical Lymphocytes

64
Q

The presence of atypical lymphocytes might be indicative of what?

A

infectious mononucleosis

65
Q

What is used to describe formed or benign lymphocytes?

A

Reactive lymphocytes

66
Q

What are some causes for reactive lymphocytes?

A
  1. viral
  2. bacterial
  3. drug reaction
67
Q

The monocyte is formed in the ____, transported by the ____, and migrates into the ____, where it transforms into a histiocyte or macrophage.

A
  1. Marrow
  2. Blood
  3. Tissues
68
Q

The blood monocytes and tissue macrophages make up a mononuclear phagocyte system also know as what?

A

Reticuloendothelial System

Class 22010 Lab (7 decks)

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