PVD Flashcards
What is the normal GFR?
90-120
What is the normal CRP and what is indicated with elevation?
<3; inflammation
What is the normal homocysteine level?
<15
Sodium restriction
<2400mg but 1500 is ideal
How do diuretics work to decrease blood pressure?
They cause volume depletion, sodium excretion, and vasodilation of peripheral arterioles.
Side effect of thiazides
Decreased libido in men
What are three examples of diuretics?
Hydrochlorothiazide
Furosemide
Spironolactone
How do calcium channel blockers work to decrease Bp?
Interfere with the movement of calcium ions across the membrane, slow the rate of contraction of the heart, and relax the smooth muscle of blood vessels resulting in vasodilation.
What are 4 calcium channel blockers?
Amlodipine (grapefruit safe)
Diliazem
Nifedipine
Verapamil
What are 3 examples of ACE inhibitors?
Benazepril
Captopril
Enalapril
What are 2 angiotensin 2 receptor blockers?
Losartan
Valsartan
What is a precaution of angiotensin 2 receptor blockers?
Avoid foods high in K
What is an example of an aldosterone receptor agonist? What are side effects or precautions?
Eplerenone
Do not take with grapefruit juice or St. John’s wart.
Can cause low sodium and high potassium
What do beta adrenergic blockers do?
Inhibit cardiac response to sympathetic nerve stimulation by blocking beta receptors thus reducing heart rate, cardiac output, and Bp.
Also inhibit the release of renin
What are three beta blockers?
Propranolol
Metoprolol
Atenolol
What are some precautions with beta blockers?
Orthostatic hypotension
Fatigue, depression, and sexual dysfunction
Caution in diabetics
How do central alpha agonists work?
Stimulate receptors in brain stem resulting in reduced sympathetic outflow for CNS with a decrease in HR and peripheral vascular resistance. Very fast
What is an example of a central alpha agonist?
Clonidine
How do alpha adrenergic agents work?
Dilate the arterioles and veins. Works quickly
What are two examples of alpha adrenergic agonists?
Prazosin
Doxazosin