Pump function and cardiac cycle Flashcards

1
Q

What do neural controls of the peripheral system do?

A

Alter blood distribution to meet specific tissue demands and maintain adequate MAP by altering blood vessel diameter.

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2
Q

How do hormones affect blood pressure?

A

Chemicals, both endocrine and paracrine, influence blood pressure by acting on vascular smooth muscle or the vasomotor center.

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3
Q

Describe the cardiac cycle

right side

A

Vena cava-> right atrium-> tricuspid valve-> Right ventricle

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4
Q

Describe the cardiac cycle (left side)

A

Pulmonary vein-> Left atrium -> mitral valve-> left ventricle

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5
Q

Which side of the heart pumps blood at a higher pressure?

A

The left ventricle operates at 5x higher pressure than the right ventricle

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6
Q

What is the dicrotic notch?

A

When blood is forced into the major arteries, the walls are stretched

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7
Q

Where does most of the filling of the ventricle occur?

A

In the first third of the diastole which gives scope for increases in heart rate

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8
Q

What are the requirements of electrical conduction on the cardiac cycle?

A

Left and right atria must contract synchronously
Left and right ventricles must contract synchronously
Ventricles must contract atria

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9
Q

What is the origin of the heart beat?

A

Myogenic origin in the pacemaker cells of the sinuatrial node (SA) in the right atrium

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10
Q

What causes conduction of the heart?

A

Rudimentary conducting bundles project through the two atria to ensure rapid conduction of excitation and synchronous contraction

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11
Q

Why can the excitation not pass to the ventricles?

A

Due to insulating connective tissue except at the atrioventricular node (AV) node

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12
Q

Why is there a conduction delay at the AV node?

A

Due to the small diameter of the conducting cells, a conduction delay of 0.12 sec occurs

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13
Q

What happens once the excitation passes through the AV node?

A

It propagates very rapidly through the ventricles due to a conducting system made of large diameter conducting cells called Purkinje cells

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14
Q

Where are the Purkinje cells?

A

They are arranged in the septum into the bundle of His which then divides into right and left bundle branches

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15
Q

Where does the excitation spread from the conducting bundles?

A

Into the cardiac muscle cells (myoscytes), the membranes of which contain protein channels allowing communication between adjacent cells.

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16
Q

Where does contraction start?

A

At the septum and papillary muscles, then the apex and then moves towards the base

17
Q

Where does relaxation occur?

A

At the septum and papillary muscles, then the apex and then moves towards the base

18
Q

What are the effects of the autonomic nervous system on the heart rate?

A

Vagus nerves

Cardiac sympathetics and adrenaline

19
Q

How can vagus nerves effect the heart rate?

A

Slow heart rate (bradycardia or negative chronotropic action) by action on SA node and slow conduction throught the AV nodes (negative dromotropic action) with minimal action on the ventricles

20
Q

How can the cardiac sympathetics and adrenaline effect the heart rate?

A

Increase heart rate (tachycardia or positive chronotropic action) by action on SA node and increase conduction speed through the AV nodes (positive dromotropic action). Increased contractility of the ventricles (positiive inotropic action) with increased rate of relaxation (positive lusitropic action)

21
Q

What does having a large mass of heart with numerous cardiac cells lying parallel mean?

A

That during excitation, a sizeable electrical field is generated

22
Q

How can heart rate be measured

A

By electrocardiogram

23
Q

How is electrocardiogram recorded?

A

By attaching recording leads to the left and right wrists and left ankle

24
Q

What is the order of the cycle in an electrocardiogram?

A

P, QRS, T

25
Q

What is P?

A

Depolarisation of atria

26
Q

What is QRS?

A

Depolarisation of the ventricles (hides repolarisation of the atria)

27
Q

What is T?

A

Repolarisation of the ventricles

28
Q

What lead is the measurement cycles obtained from?

A

Lead 2 (between right wrist and left ankle)