Pulmonology Flashcards
Asthma medication associated with arrhythmias and seizures
Theophylline
Classification of asthma severity
Intermittent: FEV1 >80%
Mild persistent: FEV1 >80%, SABA more than 2 times per week, minor limitation
Moderate: FEV1 60-80%
Severe: FEV1 <60%
COPD in a 30-40 year old makes you think of this diagnosis/work-up
alpha1- antitrypsin deficiency
Hyperinflation, flat diaphragm, trapped air, bullae/blebs on CXR
Emphysema
Enlarged right heart border, increase vascular marking on CXR
Chronic bronchitis
Stages of COPD management
GOLD I: FEV1 >80- SABA and/or anticholinergic II: FEV1 50-79 Add LABA III: FEV1 30-50 Add pulmonary rehab, ?steroids IV: FEV1 <30 Add O2 therapy
Most common causes of bronchiectasis
Cystic Fibrosis (pseudomonas) most common cause
H.Flu most common cause if not CF
Cystic Fibrosis patient with bronchiectasis, What is the likely microorganism? Treatment?
Pseudomonas; Fluoroquinolone
CT reveals airway dilation, tram-track appearance, lack of tapering bronchi. What is the diagnosis?
Bronchiectasis
Treatment for Mycobacterium Avian Complex
clarithromycin + ethambutol
Manifestations of Cystic Fibrosis
GI: Meconium ileus at birth, pancreatic insufficency (foul smelling stool)
Resp: recurrent respiratory infections
Most common extrapulmonary findings of sarcoidosis
Skin: erythema nodosum, lupus pernio
LN’s: intrathoracic hilar adenopathy
Optic: uveitis
Elevated ACE makes you think of what diagnosis?
Sarcoidosis (NCG secrete ACE)
CXR/CT finding of idiopathic pulmonary fibrosis
Diffuse reticular opacities (HONEYCOMBING!)
CXR reveals nodular opacities in upper lobes, eggshell calcifications of hilar LN’s. What is the exposure?
Mining and quarry work (Silicosis!)
Byssinosis is caused from?
Long-term cotton exposure
What condition would be seen with CXR showing pleural plaques, thickening, interstitial fibrosis in lower lobes
Asbestosis
Most common mediastinal tumor
Thymoma
Characteristics of malignant pulmonary nodule
irregular, spiculated, rapid growth, cavitary with thickened walls
Where does lung cancer usually METs to?
brain, bone, liver, LN and adrenals
What are the two central lung cancers?
Squamous cell carcinoma and small cell carcinoma
Characterstics of small cell lung cancer
aggressive, central, SVC syndrome, SIADH/hyponatremia, paraneoplastic (Cushings)
Pancoast syndrome
shoulder pain, Horners syndrome, atrophy of hand/arm
seen with squamous cell carcinoma
Lung cancer associated with cavitary lesions, hyperkalemia, pancoast tumor
squamous cell carcinoma (NSCLC)
Diagnosis of bronchial carcinoid tumor
pink to purple well vascularized central tumor
Where does mesothelioma originate from
Pleura (80%)