pulmonology Flashcards

1
Q

epiglottitis- epi and etiology

A

2-7yr
HIB
GABHS, Strep pneumonia and Staph

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2
Q

clinical epiglottitis

A

abrupt onset- high fever, toxic, muffled speech, dysphagia with drool, sitting forward in tripod

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3
Q

diagnosis epiglotitis

A

cherry red swollen epiglottis

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4
Q

epiglottitis on xray

A

thumbprint on lateral

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5
Q

antibiotic for epiglottitis

A

2nd or 3rd gen. cephalosporin IV

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6
Q

if HIB infection and ppx

A

rifampin

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7
Q

laryngotrachealbronchitis (croup)

A

inflamm. and edema of the subglottic larynx, trachea, and bronchi
viral croup –> stridor - 3 months to 3 yrs - M2:1F
spasmodic - preschool age

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8
Q

viral croup can be caused by:

A
parainfluenza
RSV
rhino
adeno
influenza A and B
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9
Q

clinical pres. of viral croup

A

URI 2-3 days followed by stridor and cough
barky cough, stridor, fever –> 3-7 days
stridor worse at night with agitation

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10
Q

xray of viral croup

A

steeple sign

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11
Q

management of croup

A

supportive
cool mist
systemic corticosteroid -
racemic epinephrine if resp. distress

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12
Q

bacterial tracheitis

A

acute inflammation of the trachea - causes stridor

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13
Q

causes of bacterial tracheitis -

A

staph, strep, nontypeable H. flu

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14
Q

bronchiolitis

A

inflammation of the bronchioles - viral infection that causes inflammatory bronchiolar obstrucion
most common in

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15
Q

bronchiolitis etiology

A

RSV

less common: para, adeno, rhino, influenza

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16
Q

clinical of bronchiolitis

A
onset is gradual
tachypnea, fine rales, wheezing 
spleen and liver might enlarge
hypoxia
apnea
CXR hyperinflation - patchy infiltrates and atelectasis
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17
Q

typical causes of pneumonia in 0-3 month

A
syphilis, toxo, CMV, rubella, herpes, tb
GBS
gram - rods 
listeria 
rsv
 (afebrile) chlamydi, CMV, PCP
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18
Q

typical pneumonia in 3 months - 5 yrs causes

A

adenovirus, influenza A and B, para , RSV,

bacterial: strep pneumoniae, staph and HIB

19
Q

age >6 pneumonia cuase

A

mycoplasma pneumoniae and chlamydia pneumoniae
viruses - adenovirus, influenza A and B, parainflue
bacterial - strep. pneumoniae

20
Q

viral pneumonia presentation

A

URI - nasal congestion and rhinorrhea - then fever, cough, dyspnea

21
Q

bacterial pneumonia presentation

A

rapid onset and greater severity - fever, cough, dyspnea, without preceding URI

22
Q

viral pneumonia xray

A

interstitial infiltrates

23
Q

bacterial pneumonia xray

A

lobar consolidation

24
Q

chlamydia trachomatis - pnemonia

presentation, diagnosis

A

most common is afebrile - 1-3 months of age
stoccato-type cough
history of conjunctivitis after birth - >50%
eosinophilia and cxr with interstitial infiltrates - definitive diagnosis by culture

25
Q

how to manage chlamydia trachomatis pneumonia

A

erythromycin or azithromycin

26
Q

mycoplasma pneumoniae

A

most common in older children
low-grade fever, chills, nonproductive cough, HA, pharyngitis, malaise
cough 3-4 wks
widespread rales

27
Q

diagnosis of mycoplasma pneumonia

A

positive cold agglutinins -
cxr - bilateral diffuse infiltrates
IgM titer for mycoplasma

28
Q

manage of mycoplasma pnemonia

A

erythromycin

29
Q

who is at risk for pertussis?

A
30
Q

stages of pertussis

A
incubation 7-10 days
catarrhal stage (1-2 wks) URI + low grade fever
paroxysmal stage (2-4wks) forceful coughing and whoop - inspiatory gasp heard at the very end of a coughing fit -- might vomit post cough attack - otherwise well and afebrile
convalescent phase - (weeks to months) - paroxysmal cough continues but become less frequent and less severe over time
31
Q

diagnosis of pertussis

A

lymphocytosis

32
Q

when to give antibiotics to alter course in pertussis?

A

during the catarrhal stage or earlier

33
Q

isolation and pertussis

A

need to be on isolation until 5 days of abx

34
Q

IgE release?

A

eosinophils, histamine, mast cells, basophils

35
Q

asthma pathophys

A

smooth muscle bronchoconstriction, airway mucosal edema, increased secretions with mucous plugging, eventual airway wall remodeling and production of inflammatory mediators IgE

36
Q

cxr of asthma

A

hyperinflation
peribronchial thickening
patchy atelectasis

37
Q

CF etiology

A

AR - ch. 7

38
Q

pathophys for CF

A

abnormal ion-channel regulator protein - causes sodium and choride transport dysfunction in epithelial cells
abnormal mucus produced in airways helps create airwy obstruction inflammation and infection

39
Q

clinical present of CF

A
chronic progressive pulmonary insuff. 
pancreatic insuff. 
high sweat electrolyte 
meconium ileus at birth(20%)
FTT - recurrent chronic resp. symptoms
respiratory signs 
PFTs decreased respiratory flow rates and decrease lung volumes 
pneumonia- staph and then pseudomonas
nasal polyps and precurrent pneumonia
40
Q

diagnosis of CF

A

one or more phenotypic feature OR positive fam. history OR increased immunoreactive trypsinogen on newborn screen
- sweat chloride test
2 CF mtn
characteristic ion transport abnormality across the nasal epithelium

41
Q

management of CF

A
antibiotics
pul. toilet 
bronchodilator
pancreatic enzyme replacement - fat soluable vitamine (A, D, E, K)
anti-inflammatory and immunosuppressive
lung transplant
psychological help
42
Q

CF and mutation

A

CFTR gene ch. 7

43
Q

ddx of ALTE

A
seizure
GERD
upper airway obstruction
intracranial mass lesion
sepsis
metabolic abnormalities including electrolyte imbalance and hypoglycemia
inborn errors of metabolism
arrhythimia
abnormal central control
munchausen by proxy
nonaccidental trauma