Pulmonary Neoplasms (Handorf) Flashcards
Is may be a connection between lung cancer and ____
skrokes
What lung cancer may appear in any part of the mung
large cell undifferentiated carcinoma
**tumor is rather large by time of Dx
What lung cancers have a high likelihood to metastasize?
small cell > large cell undifferentiated > others
“scar” carcinoma
Bronchial-derived adenocarcinoma
No relation to cigarette smoking
carcinod tumors
May be multifocal, bilateral
Adenocarcinoma in situ (Bronchioloalveolar carcinoma)
virtually never seen in nonsmokers
small cell carcinoma
if the patient coughs up some tumor cells and then aspirates them, the tumor will seed wherever the cells land. Most lung cancers DO NOT spread this way.
Adenocarcinoma in situ (Bronchioloalveolar carcinoma)
Derived from neuroendocrine cells
small cell carcinoma
“Biphasic” histologic pattern
Pleural Mesothelioma
Tend to be centrally located in the lung
squamous cell carcinoma
Nuclei normally do not touch due to more cytoplasm.
Moderate amount of cytoplasm
large cell undifferentiated sarcoma
neuroendicrine neoplasms
small cell carcinoma
carcinoid
there is almost no cytoplasm, and the nuclei will characteristically mold around one another
small cell carcinoma
many mitotic figures
small cell carcinoma
no mitotic figures and small, regular nuclei
carcinoid tumor
lepidic growth pattern
Adenocarcinoma in situ (Bronchioloalveolar carcinoma)
What is carcinoid syndrome? What causes it?
a group of symptoms associated with carcinoid tumors– tumors of the small intestine, colon, appendix, and bronchial tubes in the lungs
systemic effects of vasoactive substances produces by the tumor
symptoms of carcinod syndrome
Abdominal pain that comes and goes Bright red flushing of the face Diarrhea (may be explosive and severe) Heart palpitations Hypotension Wheezing
Least correlated with smoking
Adenocarcinoma in situ (Bronchioloalveolar carcinoma)
Spreads widely through the pleural space
Pleural Mesothelioma
sometimes cavitating
large cell undifferentiated sarcoma
assc with Cushing syndrome
small cell carcinoma
keratin pearls
squamous cell
Characteristic intrabronchial spread
Adenocarcinoma in situ (Bronchioloalveolar carcinoma)