Pulmonary Circulation Flashcards
what is the pulmonary wedge pressure?
a measure to estimate the left atrial pressure
info on risk of pulmonary oedema
physiology of a high v/q?
less perfusion relative to ventilation
(less physiological dead space)
= waster ventilation = less efficient gas exchange
what causes a high v/q ratio?
pulmonary embolism
emphysema
how does a pulmonary embolism cause a high v/q ratio?
embolus blocks pulmonary blood flow = less perfusion = wasted ventilation = less gas exchange
how does emphysema cause a high v/q ratio?
emphysema = chronic destruction of alveolar elastic spaces = air spaces permanently dilated = less air perused = wasted ventilation = less gas exchange
what are clinical signs of high ventricular failure?
peripheral oedema
raised jvp
what is the average v/q ratio?
0.8
how is physiological dead space calculated?
anatomical dead space + air in alveoli that is not perfused
physiological dead space = total dead space
what causes a low v/q?
asthma
chronic bronchitis
pulmonary oedema
acute respiratory distress syndrome
pneuonica
R to L cardiac shunts
anaphylaxis
atelectasis
how does asthma cause a low v/q?
asthma = chronic inflammatory disease = smooth muscle constriction + airway narrowing = less air reach lungs
how does chronic bronchitis cause a low v/q?
chronic inflammation of bronchi = mucus accumulation + narrowing of airways = less air reach lungs
how does pulmonary oedema cause a low v/q?
pulmonary oedema = build up go fluid in lung interstitial and alveoli = less air reach lungs
how does pneumonia cause a low v/q?
infected alveoli = consolidation = less air reaches lungs
how does acute respiratory distress syndrome cause low v/q?
respiratory failure secondary to widespread infection of lung tissues = build up of fluid in alveoli = less air reach lungs
how does R to L cardiac shunts cause a low v/q?
abnormal connection between the L and R ventricles = deoxygenated blood can bypass lungs and re-enter systemic circulation = deoxygenated blood is not ventilated = no gas exchange