Control of Breathing Flashcards

1
Q

what are the muscles of forced expiration?

A

internal intercostal muscles

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2
Q

what are the accessory muscles of inspiration?

A

sternocleidomastoid muscles
serratus anterior
scalene muscles
levator scapulae

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3
Q

what are the accessory muscles of expiration?

A

internal intercostal muscles
rectus abdominus
quadrates lumborum
latissis dorsi
transversus abdominis
external oblique muscles
internal oblique muscles

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4
Q

what muscles are used in normal inspiration?

A

the external intercostal muscles support the diaphragm

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5
Q

where is the respiratory centre?

A

in the medulla and pons

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6
Q

what does the respiratory centre do?

A

controls the basic breathing pattern

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7
Q

where are central chemoreceptors found?

A

on the ventral surface of the medulla

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8
Q

where is the central expiratory centre?

A

in the ventral respiratory group in pons

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9
Q

where is the central inspiratory centre?

A

in the dorsal respiratory group in the pons

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10
Q

where are peripheral chemoreceptors for oxygen, carbon dioxide and hydrogen ions?

A

carotid and aortic bodies

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11
Q

where is the apneustic centre?

A

in the lower pons

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12
Q

what does the pro-botzinger complex do ?

A

it is the medullary rhythm generator
regulates normal bretahing

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13
Q

how do peripheral chemoreceptors control ventilation rate?

A

they respond to the pO2 in arterial blood
also respond to H+ levels in CSF
- central chemoreceptors fire in response to H+ ions and increase ventilation

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14
Q

what are H+ levels in CSF a proximal measure of ?

A

PCO2 in blood
CO2 diffuses from blood into the CSF forming H+ ions

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15
Q

how do peripheral chemoreceptors control repspiratory rate?

A

they are sensitive to fluctuations in CSF fluid pH
- pH decrease = increase RR
- pH increase = decrease RR
respond to PCO2
- PCO2 increases = increase RR
can repsond to PO2, but not as sensitive to it
- needs to fall below 60mmHg

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16
Q

who is more leikyl to rely on hypoxic drive to breathe appropriately?

A

those with chronic CO2 retention membrane processes

17
Q

what mediates parasympathetic activity?

A

muscarinic receptors activated by acetylcholine

18
Q

what activates muscarinic receptors?

A

acetylcoline

19
Q

what do muscarinic receptors mediate?

A

parasympathetic activity