pulmonary blood supply and gas exchange Flashcards
what supplies lungs with oxygen
bronchial circulation
what does pulmomary circulation do broadly
takes C02 to lungs and picks up oxygen
what kind of system is pulmonary
high flow low pressure
normal arterial PO2
100mmHg
13.3kPa
normal arterial PCO2
40mmHg
5.4kPa
normal venous PO2
40mmHg
5.3kPa
normal venous PCO2
46mmHg
6.2kPa
the rate diffusion across the membrane is
- directly proportional to the partial pressure gradient
- directly proportional to gas solubility
- directly proportional to available surface area
- inversely proportional to thickness of membrane
- most rapid over short distances
V/Q relationship at base of lung
blood flow is higher than ventilation as arterial pressure exceeds alveolar pressure + alveoli are compressed
V/Q relationship at apex of lungs
blood flow is less that ventilation as arterial pressure is less than alveolar pressure + arterioles are compressed
autoregulation when blood flow>ventilation
PCO2 increased and PO2 decreases. Blood moving past this area doesnt get oxygenated –> SHUNT
Inc PCO2 causes milf bronchodilation and vessels contrict to divert blood to better ventilated areas
(this only happens pulmonary circulation - in systemic there is dilation in hypoxic areas)
autoregulation when ventilation>blood flow
increase alveolar PaO2 –> pulmonary vasodilation
decrease PaCO2 –> mild bronchial constrictoin
shunt
passage of blood throigh areas of lung that are poorly ventilated
alveolar dead space
alveoli that are ventilated but not perfused
physiological dead space
alveolar DS + anatomical DS